Drug Mechanisms

#	Molecule Aladdin ID	Cas Number	产品编号	Parent Molecule Name	Parent Molecule Type	作用机制	Max Phase	First Approval	USAN Stem	Target Aladdin ID	Target Name	Action Type	Target Type	Target Organism	Binding Site Name	参考文献
1.	硫酸茚地那韦	157810-81-6	I303016	INDINAVIR SULFATE	Small molecule	Human immunodeficiency virus type 1 protease inhibitor	4.0	1996	-vir	ALA243	人体免疫缺陷病毒 1 型蛋白酶	INHIBITOR	单一蛋白质	人类免疫缺陷病毒 1		EMA: [1]
2.	ALA2096651			MANGAFODIPIR TRISODIUM	Small molecule	Diagnostic	4.0	1997				na	na	na		EMA: [1]
3.	尿素-¹³C	58069-82-2	U475802	UREA C 13	Small molecule	Diagnostic agent	4.0	1996				na	na	na		EMA: [1]
4.	ALA2108512			HEPATITIS B IMMUNE GLOBULIN	Unknown	Surface antigen (HBsAg) binding agent	4.0	2009	-bulin	ALA5308521	表面抗原（HBsAg）	BINDING AGENT	单一蛋白质	乙型肝炎病毒		EMA: [1]
5.	levomethadyl acetate	1477-40-3	L611510	LEVOMETHADYL ACETATE	Small molecule	Mu opioid receptor agonist	4.0	1993		ALA233	阿片受体	AGONIST	单一蛋白质	人		Other: [1]
6.	全氟正戊烷	678-26-2	P281758	PERFLENAPENT	Small molecule	Ultrasound contrast agent	4.0	1998				na	na	na		PubMed: [1]
7.	ALA5315125			DUVELISIB MONOHYDRATE	Small molecule	PI3-kinase p110-gamma subunit inhibitor	4.0	2018	-lisib	ALA3267	PI3 激酶 p110-γ亚基	INHIBITOR	单一蛋白质	人		EMA: [1]
8.	ALA5315125			DUVELISIB MONOHYDRATE	Small molecule	PI3-kinase p110-delta subunit inhibitor	4.0	2018	-lisib	ALA3130	PI3 激酶 p110-delta 亚基	INHIBITOR	单一蛋白质	人		EMA: [1]
9.	ALA5315123			DIFELIKEFALIN ACETATE	Protein	Kappa opioid receptor agonist	4.0	2021	-kef-	ALA237	Kappa 阿片受体	AGONIST	单一蛋白质	人		EMA: [1]
10.	ALA5315122			BORTEZOMIB D-MANNITOL	Small molecule	26S proteasome inhibitor	4.0	2015	-zomib	ALA2364701	26S 蛋白酶体	INHIBITOR	蛋白质复合物	人	Binds the chymotrypsin-like subunit of the proteasome	EMA: [1]
11.	ALA5315121			TECOVIRIMAT MONOHYDRATE	Small molecule	Envelope phospholipase OPG057 inhibitor	4.0	2018	-vir-	ALA5308523	包膜磷脂酶 OPG057	INHIBITOR	单一蛋白质	猴痘病毒		EMA: [1]
12.	ALA5315121			TECOVIRIMAT MONOHYDRATE	Small molecule	Envelope phospholipase OPG057 inhibitor	4.0	2018	-vir-	ALA5308524	包膜磷脂酶 OPG057	INHIBITOR	单一蛋白质	牛痘病毒		EMA: [1]