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活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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A123660-5mg |
5mg |
现货 ![]() |
| |
A123660-25mg |
25mg |
现货 ![]() |
| |
A123660-100mg |
100mg |
现货 ![]() |
|
别名 | 阿曼托黄酮 |
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英文别名 | Amentoflavone | 1617-53-4 | Didemethyl-ginkgetin | 3',8''-Biapigenin | Amenthoflavone | Tridemethylsciadopitysin | MLS000574827 | CHEBI:2631 | 9I1VC79L77 | MFCD00017470 | NSC-295677 | 8-[5-(5,7-dihydroxy-4-oxo-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)ch |
规格或纯度 | ≥99.0%(HPLC) |
英文名称 | Amentoflavone |
生化机理 | Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site. |
储存温度 | 2-8°C储存 |
运输条件 | 冰袋运输 |
产品介绍 |
Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site. Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site. |
IUPAC Name | 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
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INCHI | InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H |
InChi Key | YUSWMAULDXZHPY-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O)O |
Isomeric SMILES | C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O)O |
WGK Germany | 3 |
PubChem CID | 5281600 |
分子量 | 538.46 |
Beilstein号 | 380244 |
Reaxy-Rn | 380244 |
溶解性 | ≥26.9 mg/mL in DMSO;insoluble in H2O;≥8.75 mg/mL in EtOH |
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分子量 | 538.500 g/mol |
XLogP3 | 5.000 |
氢键供体数Hydrogen Bond Donor Count | 6 |
氢键受体数Hydrogen Bond Acceptor Count | 10 |
可旋转键计数Rotatable Bond Count | 3 |
精确质量Exact Mass | 538.09 Da |
单同位素质量Monoisotopic Mass | 538.09 Da |
拓扑极表面积Topological Polar Surface Area | 174.000 Ų |
重原子数Heavy Atom Count | 40 |
形式电荷Formal Charge | 0 |
复杂度Complexity | 1050.000 |
同位素原子数Isotope Atom Count | 0 |
定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
所有立体化学键的总数The total count of all stereochemical bonds | 0 |
共价键合单元计数Covalently-Bonded Unit Count | 1 |
WGK Germany | 3 |
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Reaxy-Rn | 380244 |
个人防护装备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |