Amylin (8-37) (human) (trifluoroacetate salt)

截短的胰岛淀粉样多肽肽和胰岛淀粉样多肽生物活性的竞争性拮抗剂

CAS编号: 135702-23-7(free base)
分子式: C₁₃₈H₂₁₆N₄₂O₄₅ • XCF₃COOH
分子量: 3183.49(free base)

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
A276330-1mg	1mg	期货
A276330-2.5mg	2.5mg	期货
A276330-5mg	5mg	期货

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	IAPP (8-37) (human)(free base)
英文别名	Islet Amyloid Polypeptide (8-37) (human)(free base)
规格或纯度	≥95%
英文名称	Amylin (8-37) (human) (trifluoroacetate salt)
储存温度	-20°C储存,干燥
运输条件	超低温冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，这些产品最多可以使用一周。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	Amylin (8-37), human 是人胰淀素的一个片段。Amylin (8-37), human 在大鼠离体肠系膜阻力动脉中表现出直接的血管舒张作用。人胰淀素是一种由胰腺 β 细胞分泌的小激素，会在胰岛素缺乏的代谢条件下形成聚集物，是 II 型糖尿病的病理特征。氨基酸序列：Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human has direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus Product Describtion: Amylin (8-37) is a peptide fragment of amylin . It inhibits osteoblast proliferation, but not bone resorption, induced by full-length human amylin and does not act as an agonist at amylin receptors. Amylin (8-37) induces formation of polymorphic fibrils containing coiled and laterally-associated sheet structures. It is cytotoxic to RINm5F islet β-cells in vitro when used at a concentration of 25 µM, an effect that is inversely correlated with mature fibril content.