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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab190041-10μg |
10μg |
期货  |
| |
| Ab190041-25μg |
25μg |
期货 |
| |
| Ab190041-100μg |
100μg |
期货 |
|
| 产品名称 | Integrin beta 7 Rat mAb (AF647) |
|---|---|
| 规格或纯度 | ExactAb™, Validated, 0.5 mg/mL |
| 生化机理 | Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin. |
| 宿主种属 | Rat |
| 特异性 | Integrin beta 7 |
| 种属反应性 | Human,Mouse |
| 免疫原 | TK1 cells |
| 阳性对照 | Flow: Human peripheral blood lymphocytes. |
| 偶联 | Alexa Fluor® 647 |
| 克隆类型 | Monoclonal |
|---|---|
| 克隆号 | FIB504 |
| Format | Whole IgG |
| 亚型 | Rat IgG2a |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300 |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 0.5 mg/mL |
| 储存温度 | 2-8°C储存,避光,禁止冻结 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
Integrin beta 7 Rat mAb (AF647) (Ab190041) - Flow Cytometry
Flow cytometry analysis of Integrin beta 7 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Integrin beta 7 Rat mAb (AF647) (Ab190041) at 0.3μg/test for 1 hour at 4°C. Left panel - Rat IgG (AF647) (Ab190071).
Integrin beta 7 Rat mAb (AF647) (Ab190041) - Flow Cytometry
Flow cytometry analysis of Integrin beta 7 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Integrin beta 7 Rat mAb (AF647) (Ab190041) at 0.3μg/test for 1 hour at 4°C. Blue - Rat IgG (AF647) (Ab190071). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow |
≤0.3 μg/test,
the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume
|
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1012313 |
分析证书 | 24-10-17 | Ab190041 |
| ZJ24F1012312 |
分析证书 | 24-10-17 | Ab190041 |
| ZJ24F1012311 |
分析证书 | 24-10-17 | Ab190041 |
| ZJ24R0901103 |
分析证书 | 24-09-27 | Ab190041 |
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