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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab190236-10μg (试用装) 申请此免费试用装（?） 作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！
|
10μg |
现货  |
| |
| Ab190236-25μg |
25μg |
现货 |
| |
| Ab190236-100μg |
100μg |
现货 |
|
| 产品名称 | CD31 Rat mAb (APC) |
|---|---|
| 别名 | 血小板内皮细胞粘附分子1(PECAM1)抗体 | CD31抗体 | 交联别藻蓝蛋白偶联的大鼠抗小鼠CD31抗体 |
| 英文别名 | Cd31 | Pecam | adhesion molecule | CD31 antigen | CD31/EndoCAM | EndoCAM | FLJ34100 | FLJ58394 | GPIIA' | PECA1 | PECAM1 | PECAM-1 | PECAM-1, CD31/EndoCAM | platelet endothelial cell adhesion molecule | platelet endothelial cell adhesion molecule-1 | plat |
| 规格或纯度 | ExactAb™, Validated, 0.5 mg/mL |
| 生化机理 | Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC). |
| 宿主种属 | Rat |
| 特异性 | CD31 |
| 种属反应性 | Mouse |
| 免疫原 | C3H/HeJ mouse hematopoietic progenitor cell line 3 |
| 阳性对照 | Flow: C57BL/6 mouse splenocytes. |
| 偶联 | APC |
| 克隆类型 | Monoclonal |
|---|---|
| 克隆号 | 390 |
| Format | Whole IgG |
| 亚型 | Rat IgG2a |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300. |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 0.5 mg/mL |
| 储存温度 | 2-8°C储存,避光,禁止冻结 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
CD31 Rat mAb (APC) (Ab190236) - Flow Cytometry
Flow cytometry analysis of CD31 expression by C57BL/6 mouse splenocytes (red) compared to an isotype control (blue). Cells were stained with CD31 Rat mAb (APC) (Ab190236) at 0.04μg/test for 1 hour at 4°C. Blue - Rat IgG Isotype Control Antibody (APC) (Ab180313). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow |
≤0.3 μg/test,
the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume
|
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| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0910471 |
分析证书 | 24-09-10 | Ab190236 |
| ZJ24F0910470 |
分析证书 | 24-09-10 | Ab190236 |
| ZJ24F0910469 |
分析证书 | 24-09-10 | Ab190236 |
| ZJ24R0800952 |
分析证书 | 24-08-23 | Ab190236 |
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