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Alemtuzumab (anti-CD52), Antibody of CD52

    应用:
  • Animal Model
  • ELISA
  • Flow Cyt
  • Functional Assay
功能和特点
  • 种属反应性: Human
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

关闭

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab170481-100μg
100μg 现货 Stock Image
Ab170481-1mg
1mg 现货 Stock Image
Ab170481-5mg
5mg 现货 Stock Image
Ab170481-10mg
10mg 期货 Stock Image

基本信息

产品名称 Alemtuzumab (anti-CD52), Antibody of CD52
别名 阿伦单抗
英文别名 Alemtuzumab|Cambridge pathology 1 antigen antibody|CAMPATH 1 antibody|CAMPATH 1 antigen antibody|CAMPATH-1 antigen antibody|CD 52 antibody|CD52 antibody|CD52 antigen antibody|CD52 molecule antibody|CD52_HUMAN antibody|CDw52 antibody|CDW52 antigen antibody
规格或纯度 ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot
特异性 CD52
应用 ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
种属反应性 Human
偶联 Unconjugated
作用类型 抑制剂
作用机制 Antibody of CD52

AI解读

产品属性

抗体类型 Primary antibody
克隆类型 Recombinant
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 27.2 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 194.0 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
来源 CHO supernatant
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 Lot by Lot
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS编号和信息 216503-57-0

图片

Alemtuzumab (anti-CD52) (Ab170481) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD52 with Alemtuzumab (anti-CD52) (Ab170481) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).

Alemtuzumab (anti-CD52) (Ab170481) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD52 (red) with Alemtuzumab (anti-CD52) (Ab170481) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Alemtuzumab (anti-CD52) (Ab170481) - SEC
The purity of Alemtuzumab (anti-CD52) (Ab170481) is more than 95% verified by HPLC.

关联靶点(人)

CD52 Tclin CAMPATH-1抗原(CAMPATH-1 antigen) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

技术规格说明书

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0303663 分析证书 24-03-25 Ab170481
ZJ24F0303662 分析证书 24-03-25 Ab170481
ZJ24F0303661 分析证书 24-03-25 Ab170481

此产品的引用文献

1. Crowe JS, Hall VS, Smith MA, Cooper HJ, Tite JP.  (1992)  Humanized monoclonal antibody CAMPATH-1H: myeloma cell expression of genomic constructs, nucleotide sequence of cDNA constructs and comparison of effector mechanisms of myeloma and Chinese hamster ovary cell-derived material..  Clin Exp Immunol,  87  (1): (105-10).  [PMID:1339322] [10.1021/op500134e]
2. Giovannoni G, Cohen JA, Coles AJ, Hartung HP, Havrdova E, Selmaj KW, Margolin DH, Lake SL, Kaup SM, Panzara MA et al..  (2016)  Alemtuzumab improves preexisting disability in active relapsing-remitting MS patients..  Neurology,  87  (19): (1985-1992).  [PMID:27733571] [10.1021/op500134e]

参考文献

1. Crowe JS, Hall VS, Smith MA, Cooper HJ, Tite JP.  (1992)  Humanized monoclonal antibody CAMPATH-1H: myeloma cell expression of genomic constructs, nucleotide sequence of cDNA constructs and comparison of effector mechanisms of myeloma and Chinese hamster ovary cell-derived material..  Clin Exp Immunol,  87  (1): (105-10).  [PMID:1339322] [10.1021/op500134e]
2. Giovannoni G, Cohen JA, Coles AJ, Hartung HP, Havrdova E, Selmaj KW, Margolin DH, Lake SL, Kaup SM, Panzara MA et al..  (2016)  Alemtuzumab improves preexisting disability in active relapsing-remitting MS patients..  Neurology,  87  (19): (1985-1992).  [PMID:27733571] [10.1021/op500134e]

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