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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| R128623-100mg |
100mg |
现货  |
|
| 英文别名 | 9001-99-4 | Nuclease, ribo- | L-HISTIDINE, N-beta-ALANYL- | 2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid | 9001-73-4 | DL-(3-aminopropanoyl)histidine | 108333-82-0 | 2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid | beta-Alanylhistidine | L-Histid |
|---|---|
| 规格或纯度 | ≥1,000 units/mg dry weight |
| 英文名称 | Ribonuclease B from bovine pancreas |
| 单位定义 | One Kalnitsky Unit causes an increase in absorbance of 1.0 at 260nm at 37°C and pH 5.0 when yeast ribosomal RNA is hydrolyzed to acid soluble oliognucleotides. One Kunitz unit equals 50 Worthington units. |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
Pancreatic ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5. Ribonuclease B has a molecular weight of 14,700 ± 300 daltons. It is a glycoprotein which possesses an amino acid composition indistinguishable from that of RNase A. It contains 6 residues of mannose and 2 residues of N-acetylglucosamine per molecule. It is a glycosylated derivative of RNase A. Ribonuclease is inhibited by heavy metal ions and it is competitively inhibited by DNA. Since Molecular Biology Grade RNase A (Product R128619) is essentially free of DNase and protease activities, this product is useful in removing RNA from DNA in nucleic acid work and where other enzymes are used or where intact proteins must be recovered. Product Describtion: Pancreatic ribonuclease (RNase I) catalyzes cleavage of the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide forming a 2',3'-cyclic phosphate which may then be hydrolyzed to the corresponding 3'-nucleoside phosphate. Ribonuclease A has a molecular weight of 13,700 daltons. It operates in an optimum pH range of 7.0-7.5. Ribonuclease B has a molecular weight of 14,700 ± 300 daltons. It is a glycoprotein which possesses an amino acid composition indistinguishable from that of RNase A. It contains 6 residues of mannose and 2 residues of N-acetylglucosamine per molecule. It is a glycosylated derivative of RNase A. Ribonuclease is inhibited by heavy metal ions and it is competitively inhibited by DNA. Since Molecular Biology Grade RNase A (Product R128619) is essentially free of DNase and protease activities, this product is useful in removing RNA from DNA in nucleic acid work and where other enzymes are used or where intact proteins must be recovered.R128623 is a partially purified preparation containing a mixture of RNase A and RNase B. |
| 酶学委员会编号 | I.U.B.: 3.1.27.5 |
|---|---|
| Isomeric SMILES | C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN |
| PubChem CID | 9369 |
| 敏感性 | 易潮湿 |
|---|---|
| 分子量 | 226.230 g/mol |
| XLogP3 | -4.000 |
| 氢键供体数Hydrogen Bond Donor Count | 4 |
| 氢键受体数Hydrogen Bond Acceptor Count | 5 |
| 可旋转键计数Rotatable Bond Count | 6 |
| 精确质量Exact Mass | 226.107 Da |
| 单同位素质量Monoisotopic Mass | 226.107 Da |
| 拓扑极表面积Topological Polar Surface Area | 121.000 Ų |
| 重原子数Heavy Atom Count | 16 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 259.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS08 |
|---|---|
| 信号词 | Danger |
| 危险声明 |
H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P501: 将内容物/容器处理到。。。 P284: 如果通风不良，请佩戴呼吸防护装置。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P342+P316: 如果出现呼吸道症状：立即寻求急救。 |
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