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Recombinant Human CD46 Protein

功能和特点
  • 表达系统: HEK293
  • Accession #: P15529
  • 蛋白标签: C-His
  • 生物活性: Immobilized Human CD46 Protein at 1μg/mL (100 μL/well) can bind CD46 antibody with a linear range of 0.2-3.8 ng/mL.
  • 内毒素水平: <0.1 EU/μg
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp144024-10μg
10μg 现货 Stock Image
rp144024-50μg
50μg 现货 Stock Image
rp144024-100μg
100μg 现货 Stock Image
rp144024-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human CD46 Protein
别名 AHUS2; Antigen defined by monoclonal antibody TRA 2 10; Antigen identified by monoclonal antibody TRA 2 10; CD46; CD46 antigen; CD46 antigen complement regulatory protein; CD46 molecule; CD46 molecule complement regulatory protein; Complement membrane cof
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity

≥95% (SDS-PAGE)

Endotoxin level

<0.1 EU/μg

Function

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

生物活性 Immobilized Human CD46 Protein at 1μg/mL (100 μL/well) can bind CD46 antibody with a linear range of 0.2-3.8 ng/mL.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 Human
氨基酸 35-328 aa
序列 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDHHHHHH
纯度 ≥95% (SDS-PAGE)
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # P15529
来源 Recombinant
预测分子量 33 kDa
SDS-PAGE 55-60 kDa,under reducing conditions

AI解读

图片

Recombinant Human CD46 Protein (rp144024) - Protein Bioactivity
Immobilized Recombinant Human CD46 Protein (rp144024) at 1.0 μg/mL can bind CD46 antibody with a linear range of 0.2 - 3.8 ng/mL.

Recombinant Human CD46 Protein (rp144024) - SDS-PAGE
3 μg/lane of Recombinant Human CD46 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 55.0 kDa.


产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Store at -20~-80℃ for more than 1 year. Upon delivery aliquot. Avoid freeze/thaw cycle.

技术规格说明书

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C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0404954 分析证书 24-04-30 rp144024
ZJ24F0404953 分析证书 24-04-30 rp144024
ZJ24F0404952 分析证书 24-04-30 rp144024

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