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Recombinant Human CD47 Protein

功能和特点
  • 表达系统: HEK293
  • Accession #: Q08722
  • 蛋白标签: C-Fc
  • 生物活性: 1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a f
  • 内毒素水平: <1.0 EU/µg
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp144028-10μg
10μg 现货 Stock Image
rp144028-50μg
50μg 现货 Stock Image
rp144028-100μg
100μg 现货 Stock Image
rp144028-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human CD47 Protein
别名 重组人CD47蛋白 | 重组人整合素关联蛋白
英文别名 antigen identified by monoclonal 1D8 | Antigenic surface determinant protein OA3 | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | CD47 antigen | CD47 glycoprotein | CD47 molecule | CD47 | IAP | IAPintegrin associated protein |
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity
>95% (SDS-PAGE)
Endotoxin level
<1.0 EU/μg
Function
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

生物活性 1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a f
内毒素水平 <1.0 EU/µg
表达系统 HEK293
种属 Human
氨基酸 19-139 aa
序列 QLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVSWFSPALEVLFQGPEPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
纯度 >95% (SDS-PAGE)
蛋白标签 C-Fc
无载体 Yes
无动物源 Yes
Accession # Q08722
来源 Recombinant
预测分子量 40.7 kDa
SDS-PAGE 59.3 kDa, under reducing conditions; 109.3 kDa, under non-reducing conditions.

AI解读

图片

Recombinant Human CD47 Protein (rp144028) - Protein Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC₅₀ of human CD47 Protein is 50.0 - 200.0 ng/mL.

Recombinant Human CD47 Protein (rp144028) - ELISA
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC₅₀ of 10.34 ng/mL. 

Recombinant Human CD47 Protein (rp144028) - SDS-PAGE
3 μg/lane of Recombinant Human CD47 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 59.3 kDa under reducing conditions and 109.3 kDa under non-reducing conditions.

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from sterile PBS, 5% Trehalose, 5% Mannitol, 0.01% Tween-80, pH7.4.
复溶 It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25mg/mL.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Samples are stable for twelve months from date of receipt at -20℃ to -80℃. Upon delivery aliquot. Avoid freeze/thaw cycle.

技术规格说明书

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ23F1101861 分析证书 23-12-01 rp144028
ZJ23F1101860 分析证书 23-12-01 rp144028
ZJ23F1101859 分析证书 23-12-01 rp144028

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