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Recombinant Human Cystatin C Protein

功能和特点
  • 表达系统: E. coli
  • Accession #: P01034
  • 蛋白标签: N-His
  • 生物活性: Testing in progress
  • 内毒素水平: <1 EU/μg
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp169603-10μg (试用装)
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10μg 现货 Stock Image
rp169603-50μg
50μg 现货 Stock Image
rp169603-100μg
100μg 现货 Stock Image
rp169603-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human Cystatin C Protein
别名 重组人TRAIL/TNFSF10蛋白
英文别名 AD 8 | AD8 | Amyloid angiopathy and cerebral hemorrhage | ARMD11 | bA218C14.4 | bA218C14.4 (cystatin C) | Cst 3 | Cst3 | CST3 protein | Cystatin 3 | Cystatin-3 | Cystatin-C | Cystatin3 | CystatinC | CYTC_HUMAN | Epididymis secretory protein Li 2 | Gamma t
规格或纯度 Carrier Free, ≥95%(SDS-PAGE)
产品介绍


Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein that has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.

生物活性 Testing in progress
内毒素水平 <1 EU/μg
表达系统 E. coli
氨基酸 27-146 aa
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # P01034
来源 Recombinant
预测分子量 17.4 kDa
SDS-PAGE 17.1 kDa, under reducing conditions; 17.1 kDa, under non-reducing conditions

AI解读

图片

Recombinant Human Cystatin C Protein (rp169603) - SDS-PAGE
2 μg/lane of Recombinant Human Cystatin C Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 17.1 kDa.

产品规格参数

物理外观 Liquid
储存缓冲液 20mM Tris, 100mM NaCl, 20% Glycerol, pH8.0
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Store at -20°C for 1 year. Avoid freeze / thaw cycle.

技术规格说明书

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0506345 分析证书 24-05-31 rp169603
ZJ24F0506341 分析证书 24-05-31 rp169603
ZJ24F0506340 分析证书 24-05-31 rp169603

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