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Recombinant Human Hsp60 Protein

功能和特点
  • 表达系统: E. coli
  • Accession #: P10809
  • 蛋白标签: N-His
有货

库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp169616-10μg (试用装)
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10μg 现货 Stock Image
rp169616-100μg
100μg 现货 Stock Image
rp169616-1mg
1mg 现货 Stock Image

基本描述

产品名称 Recombinant Human Hsp60 Protein
别名 重组人Hsp60蛋白 | 人热休克蛋白60重组蛋白
英文别名 60 kDa chaperonin | Chaperonin 60 | CPN60 | EC 5.6.1.7 | Heat shock protein 60 | Hsp60 | HSP-60 | HuCHA60 | Mitochondrial matrix protein P1 | P60 lymphocyte protein | 60 kDa chaperonin | Chaperonin 60 (CPN60) | Heat shock protein 60 (HSP-60 | Hsp60) | HuC
规格或纯度 Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HSPD1 gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. Defects in HSPD1 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Defects in HSPD1 are the cause of leukodystrophy hypomyelinating type 4 (HLD4); also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. HSPD1 is clinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurs within the first two decades of life.

表达系统 E. coli
氨基酸 1-573 aa
纯度 >95% (SDS-PAGE)
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # P10809
来源 Recombinant
预测分子量 63.2 kDa
SDS-PAGE 62.0 kDa, under reducing conditions.

AI解读

图片

Recombinant Human Hsp60 Protein (rp169616) - SDS-PAGE
3 μg/lane of Recombinant Human Hsp60 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 62.0 kDa under reducing conditions.

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized form PBS, 8% Trahalose, pH7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Store at -20°C for 1 year, store at 2-8℃ for 1 month. Avoid freeze / thaw cycle.

技术规格说明书

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找到2个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0102577 分析证书 24-01-30 rp169616
ZJ24F0102576 分析证书 24-01-30 rp169616

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