Recombinant Human gp130 Protein

Animal Free11

Carrier Free

≥90%(SDS-PAGE)

功能和特点

表达系统: HEK293
Accession #: P40189
蛋白标签: C-His
生物活性: Testing in progress
内毒素水平: <1 EU/μg

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货号 (SKU)	包装规格	是否现货
rp183628-10μg (试用装) 申请此免费试用装（?）作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！	10μg	现货
rp183628-50μg	50μg	现货
rp183628-100μg	100μg	现货
rp183628-1mg	1mg	期货

查看相关系列

点击查看蛋白信息: IL6ST

Accession#:P40189 (2) Gene ID:3572 (2) gp130 (2) IL6ST (2)

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基本描述

产品名称	Recombinant Human gp130 Protein
别名	重组人gp130蛋白
英文别名	CD130 antigen \| CDw130 \| gp130 \| GP130 RAPS \| IL 6R beta \| IL-6 receptor subunit beta \| IL-6R subunit beta \| IL-6R-beta \| IL-6RB \| IL6 ST \| IL6RB_HUMAN \| IL6ST \| Interleukin 6 receptor subunit beta \| CD130 \| Interleukin receptor beta chain \| Interleukin-6
规格或纯度	Animal Free, Carrier Free, ≥90%(SDS-PAGE)
产品介绍	Protein Function: Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the class I cytokine receptor family. Binding of IL-6 (IL-11) to either the membrane-anchored or soluble IL-6 R (IL-11 R) initiates the association of IL-6 R (IL-11 R) with gp130 which then undergoes homo-dimerization and signal transduction. With other IL-6 family cytokines, such as LIF and OSM, signal transduction is triggered by the hetero-dimerization of gp130 and LIF R or OSM R. Gp130 is expressed in all organs examined. Soluble gp130, which apparently arises either from proteolytic cleavage or the membrane-bound receptor of from alternative splicing, has been detected in human serum. In in vitro experiments, natural or recombinant soluble gp130 has been shown to have inhibitory effects on OSM and CNTF activities. Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.
生物活性	Testing in progress
内毒素水平	<1 EU/μg
表达系统	HEK293
氨基酸	1-618 aa
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	P40189
来源	Recombinant
预测分子量	68.5 kDa
SDS-PAGE	78.5-117.8 kDa, under reducing conditions; 78.5-117.8 kDa, under non-reducing conditions

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SDS-PAGE: Recombinant Human gp130 Protein (rp183628)

Recombinant Human gp130 Protein (rp183628) - SDS-PAGE
3 μg/lane of Recombinant Human gp130 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 78.5-117.8 kDa.

产品规格参数

储存缓冲液	Lyophilized from PBS, pH 7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -20°C for 1 year. Avoid freeze / thaw cycle.

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找到4个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F0708292	分析证书	24-07-17	rp183628
ZJ24F0708291	分析证书	24-07-17	rp183628
ZJ24F0708290	分析证书	24-07-17	rp183628
ZJ24R0700776	分析证书	24-07-06	rp183628

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Recombinant Human gp130 Protein

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质检证书（CoA,COO,BSE/TSE 和分析图谱)

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