这是演示店铺,请务下单付款,避免造成你的财物损失。

为了获得访问"阿拉丁铁蛋"实时聊天框的流畅支持体验,建议您使用Chrome浏览器或选择360浏览器极速模式(如何切换极速模式?),感谢您选择我们!

扁桃苷

规格或纯度: 97%
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
A107072-1g
1g 现货 Stock Image
A107072-5g
5g 现货 Stock Image
A107072-25g
25g 现货 Stock Image
查看相关系列
二糖 化学生物学

基本描述

别名 苦杏仁甙,苦杏仁苷
英文别名 D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside D-Mandelonitrile-β-gentiobioside Laetrile
规格或纯度 97%
英文名称 Amygdalin
应用 生氰的糖苷是苦杏仁和杏仁凹点的组成部分。没有科学证据证明扁桃苷是抗癌物。最近的研究:联上瘤单克隆抗体的β−葡糖苷(β−glucoside)在瘤细胞里释放出氰,显示出很明显的细胞毒性。
运输条件 常规运输
产品介绍

lg溶于900ml乙醇及11ml沸乙醇, 易溶于沸水。UVλMeOHmax nm(ε): 268(179), 262(255), 257(256), 251198), 208(7210); IRνmax cmˉ1: 3330, 2860, 1640, 1590, 1490, 1450, 1270, 1160, 1060, 690[1]。水中溶解度:83 G/L (25°C),溶于醇、醚 植物来源:蔷薇科植物桃Prunus persica (L.)Batsch种子,巴旦杏P.am

名称和标识符

PubChem SID 488190992
EC号 249-925-3
IUPAC Name (2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile
INCHI InChI=1S/C20H27NO11/c21-6-10(9-4-2-1-3-5-9)30-20-18(28)16(26)14(24)12(32-20)8-29-19-17(27)15(25)13(23)11(7-22)31-19/h1-5,10-20,22-28H,7-8H2/t10-,11+,12+,13+,14+,15-,16-,17+,18+,19+,20+/m0/s1
InChi Key XUCIJNAGGSZNQT-JHSLDZJXSA-N
Canonical SMILES C1=CC=C(C=C1)C(C#N)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)O
WGK Germany 3
RTECS OO8450000
PubChem CID 656516
分子量 457.43
Beilstein号 66856
Reaxy-Rn 1695110

化学和物理性质

溶解性 可溶于水;微溶于酒精;不溶于乙醚、氯仿
密度 1.59
比旋光度 -40 ° (C=2, H2O)
熔点 223-226°C

安全和危险性(GHS)

象形图
ghs07

Harmful

信号词 Warning
危险声明 H302: Harmful if swallowed
预防措施声明 P501,P264,P270,P330,P301+P317
WGK Germany 3
RTECS OO8450000
Reaxy-Rn 1695110
个人防护装备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves

质检证书(COA)

质检报告(COA)

输入批号以搜索COA:

产品问答

产品问答

登录提交问题 Hover me 请先登录再提交问题
您提交该产品问题后,我们会在1-2个工作日内给您答复,您可以登录"我的账号",然后点击"我的产品问答"查看答案

参考文献

1. D W Macy.  (1977-08-01)  Amygdalin (Laetrile) and veterinary medicine..  Journal of the American Veterinary Medical Association,  171  ((3)):  (284-286).  [PMID:330478]
2. G J Strugala,A G Rauws,R Elbers.  (1986-07-01)  Intestinal first pass metabolism of amygdalin in the rat in vitro..  Biochemical pharmacology,  35  ((13)):  (2123-2128).  [PMID:3089225]
3. Jing Mu.  (2004-02-06)  [Advances in the study of amygdalin]..  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,  25  ((5)):  (366-369).  [PMID:14760843]
4. Alexander M Abdelnoor.  (2009-07-02)  Patented small molecules against psoriasis..  Expert opinion on therapeutic patents,  19  ((8)):  (1057-1071).  [PMID:19566378]
5. Ha-Jeong Kwon,Je-Hyun Lee,Seon-Pyo Hong.  (2010-03-02)  Improvement of the extraction efficiency of D-amygdalin from Armeniacae Semen powder through inactivating emulsin and suppressing the epimerization of D-amygdalin..  Archives of pharmacal research,  33  ((1)):  (81-86).  [PMID:20191348]
6. Xue-mei Li,Yi-yang Hu,Xiao-hua Duan.  (2010-04-01)  [Uniform designed research on the active ingredients assembling of Chinese medicine prescription for anti-liver fibrosis]..  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine,  30  ((1)):  (58-63).  [PMID:20353036]
7. George John,Balachandran Vijai Shankar,Swapnil R Jadhav,Praveen Kumar Vemula.  (2010-05-15)  Biorefinery: a design tool for molecular gelators..  Langmuir : the ACS journal of surfaces and colloids,  26  ((23)):  (17843-17851).  [PMID:20465204]
8. Hai-Ke Du,Fu-Cheng Song,Xin Zhou,He Li,Jian-Peng Zhang.  (2010-05-15)  [Effect of amygdalin on serum proteinic biomarker in pulmonary fibrosis of bleomycin-induced rat]..  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases,  28  ((4)):  (260-263).  [PMID:20465950]
9. Véronique J Barthet,Ray Bacala.  (2010-05-20)  Development of optimized extraction methodology for cyanogenic glycosides from flaxseed (Linum usitatissimum)..  Journal of AOAC International,  93  ((2)):  (478-484).  [PMID:20480892]
10. Carrie L Brady,Teresa Goszczynska,Stephanus N Venter,Ilse Cleenwerck,Paul De Vos,Ronald D Gitaitis,Teresa A Coutinho.  (2010-05-25)  Pantoea allii sp. nov., isolated from onion plants and seed..  International journal of systematic and evolutionary microbiology,  61  ((Pt 4)):  (932-937).  [PMID:20495023]
11. Soon-Mi Shim,Hoonjeong Kwon.  (2010-06-10)  Metabolites of amygdalin under simulated human digestive fluids..  International journal of food sciences and nutrition,  61  ((8)):  (770-779).  [PMID:20528582]
12. Geraldine A Wright,Julie A Mustard,Nicola K Simcock,Alexandra A R Ross-Taylor,Lewis D McNicholas,Alexandra Popescu,Frédéric Marion-Poll.  (2010-12-07)  Parallel reinforcement pathways for conditioned food aversions in the honeybee..  Current biology : CB,  20  ((24)):  (2234-2240).  [PMID:21129969]
13. Minfeng Fang,Zhiling Fu,Qilin Wang,Shixiang Wang,Chaoni Xiao,Xiaohui Zheng.  (2011-01-21)  [Effect of processing on metabolism of amygdalin from bitter almond in rat]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  35  ((20)):  (2684-2688).  [PMID:21246818]
14. Lishuang Yu,Hongzhi Ye,Lili Zheng,Lidian Chen,Kedan Chu,Xianxiang Liu,Xueqin Xu,Guonan Chen.  (2011-01-22)  Determination of the epimerization rate constant of amygdalin by microemulsion electrokinetic chromatography..  Electrophoresis,  32  ((2)):  (218-222).  [PMID:21254118]
15. Cui-Ping Zhang,Huo-Qing Zheng,Fu-Liang Hu.  (2011-05-04)  Extraction, partial characterization, and storage stability of β-glucosidase from propolis..  Journal of food science,  76  ((1)):  (C75-C79).  [PMID:21535657]
16. Deng Jiagang,Chunyang Li,Hailian Wang,Erwei Hao,Zhengcai Du,Chuanhong Bao,Jianzhen Lv,Yi Wang.  (2011-07-16)  Amygdalin mediates relieved atherosclerosis in apolipoprotein E deficient mice through the induction of regulatory T cells..  Biochemical and biophysical research communications,  411  ((3)):  (523-529).  [PMID:21756879]
17. Ebenezer O Farombi,Olatunde Owoeye.  (2011-07-22)  Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid..  International journal of environmental research and public health,  ((6)):  (2533-2555).  [PMID:21776245]
18. Kejin Zhu,Xiaoping Sun,Xiujuan Chang,Jianping Qin,Xinyong Lv,Zhenzhong Wang,Wei Xiao.  (2011-08-04)  [Pharmacokinetics of Guizhi Fuling capsule in Beagle dogs]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  36  ((8)):  (1015-1018).  [PMID:21809575]
19. Claudia Cervellati,Christian Paetz,Luca Dondini,Stefano Tartarini,Daniele Bassi,Bernd Schneider,Andrea Masia.  (2011-09-24)  A qNMR approach for bitterness phenotyping and QTL identification in an F1 apricot progeny..  Journal of biotechnology,  159  ((4)):  (312-319).  [PMID:21939695]
20. Stefania Milazzo,Edzard Ernst,Stephane Lejeune,Katja Boehm,Markus Horneber.  (2011-11-11)  Laetrile treatment for cancer..  The Cochrane database of systematic reviews,    ((11)(11)):  (CD005476-CD005476).  [PMID:22071824]
21. Hossein Mirmiranpour,Shahnaz Khaghani,Ali Zandieh,O Omid Khalilzadeh,Siavash Gerayesh-Nejad,Afsaneh Morteza,Alireza Esteghamati.  (2012-07-10)  Amygdalin inhibits angiogenesis in the cultured endothelial cells of diabetic rats..  Indian journal of pathology & microbiology,  55  ((2)):  (211-214).  [PMID:22771646]
22. Stephen Abban,Leon Brimer,Warda S Abdelgadir,Mogens Jakobsen,Line Thorsen.  (2012-12-25)  Screening for Bacillus subtilis group isolates that degrade cyanogens at pH 4.5-5.0..  International journal of food microbiology,  161  ((1)):  (31-35).  [PMID:23261810]
23. Paul S Böhm,June Southall,Richard J Cogdell,Jürgen Köhler.  (2013-03-01)  Single-molecule spectroscopy on RC-LH1 complexes of Rhodopseudomonas acidophila strain 10050..  The journal of physical chemistry. B,  117  ((11)):  (3120-3126).  [PMID:23445346]
24. D B Korman.  (2012-01-01)  [Alternative means of drug therapy in cancer: letril]..  Voprosy onkologii,  58  ((5)):  (698-704).  [PMID:23600293]
25. Juan J Perez.  (2013-05-09)  Amygdalin analogs for the treatment of psoriasis..  Future medicinal chemistry,  ((7)):  (799-808).  [PMID:23651093]
26. Jung-Hoon Kim,Chang-Seob Seo,Hyeun-Kyoo Shin.  (2014-03-13)  Development of validated determination of the eleven marker compounds in Gyejibokryeong-hwan for the quality assessment using HPLC analysis..  Archives of pharmacal research,  38  ((1)):  (52-62).  [PMID:24610256]
27. Jasmina Makarević,Jochen Rutz,Eva Juengel,Silke Kaulfuss,Michael Reiter,Igor Tsaur,Georg Bartsch,Axel Haferkamp,Roman A Blaheta.  (2014-08-20)  Amygdalin blocks bladder cancer cell growth in vitro by diminishing cyclin A and cdk2..  PloS one,  ((8)):  (e105590-e105590).  [PMID:25136960]
28. Mengkai Zheng,Huifen Zhou,Haitong Wan,Yu-Lin Chen,Yu He.  (2015-02-11)  Effects of herbal drugs in Mahuang decoction and their main components on intestinal transport characteristics of Ephedra alkaloids evaluated by a Caco-2 cell monolayer model..  Journal of ethnopharmacology,  164  ():  (22-29).  [PMID:25660335]
29. Soo-Jin Jeong,Hye-Sun Lim,Chang-Seob Seo,Seong-Eun Jin,Sae-Rom Yoo,Nari Lee,Hyeun-Kyoo Shin.  (2015-03-12)  Anti-inflammatory actions of herbal formula Gyejibokryeong-hwan regulated by inhibiting chemokine production and STAT1 activation in HaCaT cells..  Biological & pharmaceutical bulletin,  38  ((3)):  (425-434).  [PMID:25757924]
30. Islamiyat Folashade Bolarinwa.  (2015-07-22)  Synthesis and Characterization of Hapten-Protein Conjugates for Antibody Production against Cyanogenic Glycosides..  Journal of food protection,  78  ((7)):  (1408-1413).  [PMID:26197297]
31. Ellena S King,Dawn M Chapman,Kathleen Luo,Steve Ferris,Guangwei Huang,Alyson E Mitchell.  (2019-02-26)  Defining the Sensory Profiles of Raw Almond ( Prunus dulcis) Varieties and the Contribution of Key Chemical Compounds and Physical Properties..  Journal of agricultural and food chemistry,  67  ((11)):  (3229-3241).  [PMID:30798590]
32. Fang Hu,Yichuan Hu,Fangxin Peng.  (2019-03-20)  Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis..  AMB Express,  ((1)):  (37-37).  [PMID:30888523]
33. Takushi Miyoshi,Qianli Zhang,Takafumi Miyake,Shin Watanabe,Hiroe Ohnishi,Jiji Chen,Harshad D Vishwasrao,Oisorjo Chakraborty,Inna A Belyantseva,Benjamin J Perrin,Hari Shroff,Thomas B Friedman,Koichi Omori,Naoki Watanabe.  (2021-02-04)  Semi-automated single-molecule microscopy screening of fast-dissociating specific antibodies directly from hybridoma cultures..  Cell reports,  34  ((5)):  (108708-108708).  [PMID:33535030]
34. Michael K Appenteng,Ritter Krueger,Mitch C Johnson,Harrison Ingold,Richard Bell,Andrew L Thomas,C Michael Greenlief.  (2021-04-04)  Cyanogenic Glycoside Analysis in American Elderberry..  Molecules (Basel, Switzerland),  26  ((5)):  ().  [PMID:33806603]
35. Anne Vinther Morant,Nanna Bjarnholt,Mads Emil Kragh,Christian Hauge Kjaergaard,Kirsten Jørgensen,Suzanne Michelle Paquette,Markus Piotrowski,Anne Imberty,Carl Erik Olsen,Birger Lindberg Møller,Søren Bak.  (2008-05-10)  The beta-glucosidases responsible for bioactivation of hydroxynitrile glucosides in Lotus japonicus..  Plant physiology,  147  ((3)):  (1072-1091).  [PMID:18467457]
36. Y Turan.  (2008-09-09)  A pseudo-beta-glucosidase in Arabidopsis thaliana: correction by site-directed mutagenesis, heterologous expression, purification, and characterization..  Biochemistry. Biokhimiia,  73  ((8)):  (912-919).  [PMID:18774938]
37. Li Liu,Jin-ao Duan,Yuping Tang,Jianming Guo,Nianyun Yang,Hongyue Ma,Xuqin Shi.  (2011-11-30)  Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation..  Journal of ethnopharmacology,  139  ((2)):  (381-387).  [PMID:22123200]
38. Raquel Sánchez-Pérez,Fara Sáez Belmonte,Jonas Borch,Federico Dicenta,Birger Lindberg Møller,Kirsten Jørgensen.  (2012-02-23)  Prunasin hydrolases during fruit development in sweet and bitter almonds..  Plant physiology,  158  ((4)):  (1916-1932).  [PMID:22353576]
39. Noor M Shaik,Anurag Misra,Somesh Singh,Amol B Fatangare,Suryanarayanarao Ramakumar,Shuban K Rawal,Bashir M Khan.  (2012-10-20)  Functional characterization, homology modeling and docking studies of β-glucosidase responsible for bioactivation of cyanogenic hydroxynitrile glucosides from Leucaena leucocephala (subabul)..  Molecular biology reports,  40  ((2)):  (1351-1363).  [PMID:23079707]
40. Xiaoyun Shu,Yuping Tang,Chenxue Jiang,Erxing Shang,Xinshen Fan,Anwei Ding.  (2012-11-03)  Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations..  Molecules (Basel, Switzerland),  17  ((11)):  (12925-12937).  [PMID:23117432]
41. Yu Chen,Jinshu Ma,Fang Wang,Jie Hu,Ai Cui,Chengguo Wei,Qing Yang,Fan Li.  (2012-11-10)  Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells..  Immunopharmacology and immunotoxicology,  35  ((1)):  (43-51).  [PMID:23137229]
42. Jasmina Makarević,Jochen Rutz,Eva Juengel,Silke Kaulfuss,Igor Tsaur,Karen Nelson,Jesco Pfitzenmaier,Axel Haferkamp,Roman A Blaheta.  (2014-10-22)  Amygdalin influences bladder cancer cell adhesion and invasion in vitro..  PloS one,  ((10)):  (e110244-e110244).  [PMID:25333694]
43. Ivan M Savic,Vesna D Nikolic,Ivana M Savic-Gajic,Ljubisa B Nikolic,Svetlana R Ibric,Dragoljub G Gajic.  (2015-05-15)  Optimization of technological procedure for amygdalin isolation from plum seeds (Pruni domesticae semen)..  Frontiers in plant science,  ():  (276-276).  [PMID:25972881]
44. Wael M Elsaed.  (2019-05-18)  Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis through reduction of CD4+ cell infiltration..  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft,  224  ():  (124-132).  [PMID:31100343]
45. Bahman Moradipoodeh,Mostafa Jamalan,Majid Zeinali,Masood Fereidoonnezhad,Ghorban Mohammadzadeh.  (2020-09-16)  Specific targeting of HER2-positive human breast carcinoma SK-BR-3 cells by amygdaline-ZHER2 affibody conjugate..  Molecular biology reports,  47  ((9)):  (7139-7151).  [PMID:32929653]

计算器