Avelumab (anti-PD-L1)

功能和特点

规格或纯度: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
应用: ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
反应种属: Cynomolgus,Dog ,Human,Mouse ,Rabbit ,Rat
亚型: Human IgG1

有货

库存信息

关闭

库存信息

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关闭

货号 (SKU)	包装规格	是否现货
A412006-1mg	1mg	现货
A412006-5mg	5mg	现货
A412006-10mg	10mg	期货

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基本信息

产品名称	Avelumab (anti-PD-L1)
别名	阿维单抗; 阿维鲁单抗; Recombinant Avelumab Antibody; Avelumab; Anti-Human PD-L1, Human Antibody; Anti-PD-L1; MSB0010718C; Bavencio; B7 H antibody; B7 H1 antibody; B7 homolog 1 antibody; B7-H1 antibody; B7H antibody; B7H1 antibody; CD 274 antibody; CD-274 antibody;
英文别名	Recombinant Avelumab Antibody; Avelumab; Anti-Human PD-L1, Human Antibody; Anti-PD-L1; MSB0010718C; Bavencio; B7 H antibody; B7 H1 antibody; B7 homolog 1 antibody; B7-H1 antibody; B7H antibody; B7H1 antibody; CD 274 antibody; CD-274 antibody; CD274 antibo
规格或纯度	Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
特异性	B7-H1 / PD-L1 / CD274
应用	ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
反应种属	Cynomolgus,Dog ,Human,Mouse ,Rabbit ,Rat

产品属性

抗体类型	Primary antibody
Format	Whole IgG
亚型	Human IgG1
轻链亚型	Lambda
SDS-PAGE	28.7 kDa (Light Chain) & 50.1 kDa (Heavy Chain), under reducing conditions; 182.4 kDa, under non-reducing conditions.
纯化方法	Protein A purified
来源	CHO supernatant
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	Lot by Lot
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -80℃ for 18 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS编号和信息	1537032-82-8

IMGT/mAb-DB	512

图片

Flow Cytometry: Avelumab (anti-PD-L1) (A412006)

Avelumab (anti-PD-L1) (A412006) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling PD-L1 with Avelumab (anti-PD-L1) (A412006) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).

Flow Cytometry: Avelumab (anti-PD-L1) (A412006)

Avelumab (anti-PD-L1) (A412006) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling PD-L1 (red) with Avelumab (anti-PD-L1) (A412006) conjugated with biotin and detected with SA-PE (rp156250). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Avelumab (anti-PD-L1) (A412006)

Avelumab (anti-PD-L1) (A412006) - SEC
The purity of Avelumab (anti-PD-L1) (A412006) is more than 95% verified by HPLC.

1. Pardoll DM. (2012) The blockade of immune checkpoints in cancer immunotherapy.. Nat Rev Cancer, 12 (4): (252-64). [PMID:22437870]
2. Topalian SL, Drake CG, Pardoll DM. (2015) Immune checkpoint blockade: a common denominator approach to cancer therapy.. Cancer Cell, 27 (4): (450-61). [PMID:25858804]

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Avelumab (anti-PD-L1)

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