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Bevacizumab (anti-VEGF)

规格或纯度: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
B411998-1mg
1mg 现货 Stock Image
B411998-5mg
5mg 现货 Stock Image
B411998-10mg
10mg 期货 Stock Image

基本描述

别名 贝伐珠单抗; 贝伐单抗; Recombinant Bevacizumab Antibody; rhuMab VEGF; Avastin; Anti-Human VEGF; Humanized Antibody; Bevacizumab (Anti-Human VEGF, Humanized Antibody); Bevacizumab; EC 2.7.10.1 antibody; FLT 1 antibody; FLT antibody; Flt-1 antibody; FLT1 antibody; Fm
英文别名 Recombinant Bevacizumab Antibody; rhuMab VEGF; Avastin; Anti-Human VEGF; Humanized Antibody; Bevacizumab (Anti-Human VEGF, Humanized Antibody); Bevacizumab; EC 2.7.10.1 antibody; FLT 1 antibody; FLT antibody; Flt-1 antibody; FLT1 antibody; Fms like tyrosi
规格或纯度 Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
英文名称 Bevacizumab (anti-VEGF)
稳定性与储存 Store at -80℃ for 18 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
应用 ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
来源 CHO supernatant
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
产品介绍

Bevacizumab 是一种人源化的anti-VEGF单克隆抗体,是VEGF的抑制剂。可与所有人源VEGF-A亚型(和具有生物活性的蛋白水解片段)结合、中和。

Bevacizumab is a humanized anti-VEGF monoclonal antibody which binds to and neutralizes all human VEGF-A isoforms and bioactive proteolytic fragments.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

名称和标识符

分子量 149 kDa(Average)

质检证书(COA)

质检报告(COA)

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图片

Bevacizumab (anti-VEGF) (B411998) - ELISA
Immobilized Recombinant Human VEGF Protein (rp155965) at 1 μg/mL can bind Bevacizumab (anti-VEGF) (B411998) with the EC50 of 4.16 ng/mL.

Bevacizumab (anti-VEGF) (B411998) - SEC
The purity of Bevacizumab (anti-VEGF) (B411998) is more than 95% verified by HPLC.

产品问答

产品问答

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参考文献

1. Glade-Bender J, Kandel JJ, Yamashiro DJ.  (2003)  VEGF blocking therapy in the treatment of cancer..  Expert Opin Biol Ther,  (2):  (263-76).  [PMID:12662141]
2. Yang JC, Haworth L, Sherry RM, Hwu P, Schwartzentruber DJ, Topalian SL, Steinberg SM, Chen HX, Rosenberg SA.  (2003)  A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer..  N Engl J Med,  349  (5):  (427-34).  [PMID:12890841]
3. Tewari KS, Java JJ, Eskander RN, Monk BJ, Burger RA.  (2016)  Early initiation of chemotherapy following complete resection of advanced ovarian cancer associated with improved survival: NRG Oncology/Gynecologic Oncology Group study..  Ann Oncol,  27  (1):  (114-21).  [PMID:26487588]

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