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夫西地酸

规格或纯度: 98%
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
F134821-1g
 1g 现货 Stock Image
F134821-5g
 5g 现货 Stock Image
F134821-25g
 25g 现货 Stock Image
F134821-100g
 100g 现货 Stock Image
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类固醇类
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基本描述

规格或纯度 98%
英文名称 Fusidic Acid
生化机理 Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

Fusidic acid is bacteriostatic antibiotic that only works on gram-positive bacteria. It limits the growth of bacteria by inhibiting bacterial protein synthesis in a number of ways. It binds to the ribosome-elongation factor G complex, thereby inhibiti.A bacteriostatic antibiotic that only works on gram-positive bacteria.

Fusidic acid is bacteriostatic antibiotic that only works on gram-positive bacteria. It limits the growth of bacteria by inhibiting bacterial protein synthesis in a number of ways. It binds to the ribosome-elongation factor G complex, thereby inhibiti.
A bacteriostatic antibiotic that only works on gram-positive bacteria.

名称和标识符

PubChem SID 488194132
EC号 230-256-0
IUPAC Name (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
INCHI InChI=1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1
InChi Key IECPWNUMDGFDKC-MZJAQBGESA-N
Canonical SMILES CC1C2CCC3(C(C2(CCC1O)C)C(CC4C3(CC(C4=C(CCC=C(C)C)C(=O)O)OC(=O)C)C)O)C
WGK Germany 3
RTECS RC1350000
关联CAS 6990-06-3,751-94-0 (hydrochloride salt)
PubChem CID 3000226
NSC Number 56192
MeSH Entry Terms Acid, Fusidic;Fucithalmic;Fusidate Sodium;Fusidate, Silver;Fusidate, Sodium;Fusidic Acid;Fusidic Acid, Sodium Salt;Fusidin;Silver Fusidate;Sodium Fusidate;Sodium, Fusidate;Stanicide
分子量 516.71

化学和物理性质

溶解性 Soluble in alcohol (1:5), chloroform (1:4), ether (1:60), and ethanol (50 mg/ml). Insoluble in water.
敏感性 对热敏感
比旋光度 -7° (C=1,CHCl3)
熔点 193 °C

安全和危险性（GHS）

象形图
ghs07

Harmful
信号词 Warning
危险声明 H302: Harmful if swallowed
预防措施声明 P261
WGK Germany 3
RTECS RC1350000
Merck Index 4317
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

质检证书(COA)

质检报告(COA)

输入批号以搜索COA:

可替换产品

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参考文献

1. Jones RN, Biedenbach DJ, Roblin PM, Kohlhoff SA, Hammerschlag MR.  (2010)  Update on fusidic acid (CEM-102) tested against Neisseria gonorrhoeae and Chlamydia trachomatis..  Antimicrob Agents Chemother,  54  (10):  (4518-9).  [PMID:20660671]
2. Craft JC, Moriarty SR, Clark K, Scott D, Degenhardt TP, Still JG, Corey GR, Das A, Fernandes P.  (2011)  A randomized, double-blind phase 2 study comparing the efficacy and safety of an oral fusidic acid loading-dose regimen to oral linezolid for the treatment of acute bacterial skin and skin structure infections..  Clin Infect Dis,  52 Suppl 7  (13):  (S520-6).  [PMID:21546629]
3. Sahm DF, Deane J, Pillar CM, Fernandes P.  (2013)  In vitro activity of CEM-102 (fusidic acid) against prevalent clones and resistant phenotypes of Staphylococcus aureus..  Antimicrob Agents Chemother,  57  (9):  (4535-6).  [PMID:23774441]
4. Pushkin R, Iglesias-Ussel MD, Keedy K, MacLauchlin C, Mould DR, Berkowitz R, Kreuzer S, Darouiche R, Oldach D, Fernandes P.  (2016)  A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction..  Clin Infect Dis,  63  (12):  (1599-1604).  [PMID:27682068]

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