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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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H104510-1g |
1g |
现货 ![]() |
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H104510-5g |
5g |
现货 ![]() |
| |
H104510-25g |
25g |
现货 ![]() |
| |
H104510-100g |
100g |
现货 ![]() |
| |
H104510-250g |
250g |
现货 ![]() |
| |
H104510-500g |
500g |
现货 ![]() |
|
别名 | 4-羟基-2,2,6,6-四甲基哌啶1-氧基自由基;4-羟基-TEMPO;4-羟基哌啶醇氧自由基;4-羟基-2,2,6,6,-四甲基-4-哌啶基氧自由基;4-羟基-2,2,6,6-四甲基哌啶氮氧自由基;阻聚剂ZJ-701;4-羟基-TEMPO 自由基;哌啶醇氧化物;4-羟基-2,2,6,6-四甲基哌啶-1-氧自由基 |
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英文别名 | 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical;4-Hydroxy-TEMPO Free Radical;TEMPOL |
规格或纯度 | 98% |
英文名称 | 4-Hydroxy-TEMPO |
生化机理 | 膜可渗透的超氧化物清除剂。SOD模拟。减轻超氧阴离子和过亚硝酸盐引起的炎症。降低氧化应激。 |
应用 | 4-羟基-TEMPO(HO-TEMPO)可用作催化剂将醇氧化成相应的醛。它可用于制备TEMPO聚合物催化体系,该体系可用于多种伯醇的Anelli氧化。它可以用作合成4-(2,2,6,6-四甲基-1-氧基-4-哌啶氧基)丁基溴的起始试剂。 用于研究生物化合物和聚合物的自旋标记物。 由衍生化TEMPO丙炔醚以及随后与氟叠氮化物发生"点击"反应,制备氟标记的TEMPO衍生物。该TEMPO衍生物已被证明是用漂白剂氧化醇的高效催化剂。 自旋标记试剂,用于鉴定 NK1 受体的拮抗剂和激动剂结合位点。也可用于电子自旋共振光谱法测定心肌中活性氧的生成。TEMPOL 可保护过量表达 CYP2E1 的细胞免受花生四烯酸的毒性损伤。 |
储存温度 | 2-8°C储存,充氩 |
运输条件 | 冰袋运输 |
备注 | 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
产品介绍 |
TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies. TEMPOL is a superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, and has the ability to permeate the membrane. In the presence of TEMPOL, cerebral vessel remodeling is blocked and collagen IV mRNA expression levels are elevated in normotensive and hypertensive rat studies. TEMPOL has been shown to restore the oxidative stress and cardiac dysfunction induced by TNF-α and in PC-12 cells has revealed neuroprotective effects. Additionally, it has shown to decrease blood pressure and sympathetic nerve activity in DOCA-salt rat studies. product description: 4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic. |
EC号 | 218-760-9 |
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WGK Germany | 1 |
RTECS | TN8991000 |
PubChem CID | 137994 |
分子量 | 172.24 |
Beilstein号 | 1422990 |
Reaxy-Rn | 11328213 |
溶解性 | 易溶于乙醇、苯等有机溶剂,易溶于水。 |
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密度 | 1.187 |
敏感性 | 对光线和湿度敏感 |
闪点(℉) | 146℃ |
闪点(℃) | 146℃ |
熔点 | 69-71°C |
象形图 |
![]() Harmful |
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信号词 | Warning |
危险声明 |
H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H302: Harmful if swallowed |
预防措施声明 | P261,P305+P351+P338 |
WGK Germany | 1 |
RTECS | TN8991000 |
Reaxy-Rn | 11328213 |
Merck Index | 9141 |
个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
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