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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
I411993-1mg |
1mg | 期货 | | |
I411993-5mg |
5mg | 期货 | | |
I411993-10mg |
10mg | 期货 | |
产品名称 | Ipilimumab (anti-CTLA-4) |
---|---|
别名 | 伊匹单抗; 伊匹木单抗; MDX-010; BMS-734016; Yervoy; Ipilimumab; Ipilimumab (anti-CTLA-4); Recombinant Ipilimumab Antibody; Ipilimumab (MDX-010); ALPS5 antibody; CD 152 antibody; CD antibody; CD152 antibody; CD152 antigen antibody; CD152 isoform antibody; Celiac dis |
英文别名 | MDX-010; BMS-734016; Yervoy; Ipilimumab; Ipilimumab (anti-CTLA-4); Recombinant Ipilimumab Antibody; Ipilimumab (MDX-010); ALPS5 antibody; CD 152 antibody; CD antibody; CD152 antibody; CD152 antigen antibody; CD152 isoform antibody; Celiac disease 3 antibo |
规格或纯度 | Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated |
特异性 | CTLA-4/CD152 |
应用 | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
反应种属 | Cynomolgus,Human,Mouse |
抗体类型 | Primary antibody |
---|---|
Format | Whole IgG |
亚型 | Human IgG1 |
轻链亚型 | Kappa |
SDS-PAGE | 26.9 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 176.3 kDa, under non-reducing conditions. |
纯化方法 | Protein A purified |
来源 | CHO supernatant |
物理外观 | Liquid |
储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
防腐剂 | No |
浓度 | Lot by Lot |
储存温度 | -80℃储存,避免反复冻融 |
运输条件 | 超低温冰袋运输 |
稳定性与储存 | Store at -80℃ for 18 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
CAS编号和信息 | 477202-00-9 |
IMGT/mAb-DB | 180 |
---|---|
PubChem SID | 178103470 |
Wikipedia | Ipilimumab |
输入批号以搜索COA:
1. Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, Linette GP, Meyer N, Giguere JK, Agarwala SS et al.. (2015) Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.. N Engl J Med, 372 (21): (2006-17). [PMID:25891304] |
2. Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P et al.. (2015) Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.. N Engl J Med, 373 (1): (23-34). [PMID:26027431] |
3. Motzer RJ, Tannir NM, McDermott DF, Arén Frontera O, Melichar B, Choueiri TK, Plimack ER, Barthélémy P, Porta C, George S et al.. (2018) Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.. N Engl J Med, 378 (14): (1277-1290). [PMID:29562145] |