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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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K287947-10mg |
10mg |
现货 ![]() |
| |
K287947-50mg |
50mg |
现货 ![]() |
| |
K287947-250mg |
250mg |
现货 ![]() |
|
别名 | (±)-2-(1H-苯并咪唑-2-基硫基)丙酸2-[((5-溴-2-羟基苯基)亚甲基]酰肼 |
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英文别名 | (±)-2-(1H-benzimidazol-2-ylthio)propanoic acid 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;(E)-2-(1H-Benzodimidazol-2-ylthio)-N-(5-bromo-2-hydroxybenzylidene)propanehydrazide;(S,Z)-2-((1H-benzo[d]imidazol-2-yl)thio)-N'-((3-bromo-6-oxocyclohexa-2,4-die |
规格或纯度 | 98% |
英文名称 | KH 7 |
生化机理 | KH7 is a selective inhibitor of soluble adenylyl cyclase. Soluble adenylyl cyclase (sAC) is an ubiquitously expressed, essential component of cAMP-signaling. |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 |
KH7 has been used:
as a soluble adenyl cyclase (sAC) antagonist to study its effect on the signaling pathway mediated by the action of transient receptor type 1 (TRPV1) in sperm cells.
as a selective sAC antagonist to study its effect on the signaling pathway of proton gated channels (HV1) induced action in sperm cells.
as a sAC inhibitor to study its effects on cAMP increase in monophosphorylated myosin light chain (pMLC). |
IUPAC Name | 2-(1H-benzimidazol-2-ylsulfanyl)-N-[(E)-(5-bromo-2-hydroxyphenyl)methylideneamino]propanamide |
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INCHI | InChI=1S/C17H15BrN4O2S/c1-10(25-17-20-13-4-2-3-5-14(13)21-17)16(24)22-19-9-11-8-12(18)6-7-15(11)23/h2-10,23H,1H3,(H,20,21)(H,22,24)/b19-9+ |
InChi Key | WILMXUAKQKGGCC-DJKKODMXSA-N |
Canonical SMILES | CC(C(=O)NN=CC1=C(C=CC(=C1)Br)O)SC2=NC3=CC=CC=C3N2 |
PubChem CID | 135496218 |
分子量 | 419.3 |
PubChem CID | 135496218 |
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CAS Registry No. | 330676-02-3 |
溶解性 | 溶于DMSO, 最高浓度 (mg/mL): 41.93, 最高浓度(mM): 100 |
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象形图 |
![]() Toxic |
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信号词 | Danger |
危险声明 |
H301: Toxic if swallowed |
预防措施声明 | P321,P405,P501,P264,P270,P330,P301+P316 |
RIDADR | UN28116.1/PGIII |
输入批号以搜索COA:
1. Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M, Miyamoto C, Zippin JH, Kopf GS, Suarez SS et al.. (2005) The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization.. Dev Cell, 9 (2): (249-59). [PMID:16054031] |