Pertuzumab (anti-HER2)

功能和特点

规格或纯度: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
应用: ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
反应种属: Human,Mouse ,Rat
亚型: Human IgG1

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
P412000-1mg	1mg	现货
P412000-5mg	5mg	现货
P412000-10mg	10mg	期货

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erb-b2 receptor tyrosine kinase 2 Antibody

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基本信息

产品名称	Pertuzumab (anti-HER2)
别名	帕妥株单抗; 帕妥珠单抗; Recombinant Pertuzumab Antibody; Omnitarg, 2C4; Anti-Human HER2, Humanized Antibody; Pertuzumab; Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody; C erb B2/neu protein antibody; C
英文别名	Recombinant Pertuzumab Antibody; Omnitarg, 2C4; Anti-Human HER2, Humanized Antibody; Pertuzumab; Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody; C erb B2/neu protein antibody; CD340 antibody;
规格或纯度	Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
特异性	ERBB2/HER2/CD340
应用	ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
反应种属	Human,Mouse ,Rat

产品属性

抗体类型	Primary antibody
Format	Whole IgG
亚型	Human IgG1
轻链亚型	Kappa
SDS-PAGE	145.44 kDa
纯化方法	Protein A purified
来源	CHO supernatant
物理外观	Liquid
储存缓冲液	Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	Lot by Lot
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -80℃ for 18 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS编号和信息	380610-27-5

数据库链接

Wikipedia	Pertuzumab
IMGT/mAb-DB	80
PubChem SID	178101741
Reactome Reaction	R-HSA-9665726, R-HSA-9665703, R-HSA-9665708
Reactome Drug	R-ALL-9665971

Wikipedia

Pertuzumab

IMGT/mAb-DB

PubChem SID

178101741

Reactome Reaction

R-HSA-9665726, R-HSA-9665703, R-HSA-9665708

Reactome Drug

R-ALL-9665971

图片

Flow Cytometry: Pertuzumab (anti-HER2) (P412000)

Pertuzumab (anti-HER2) (P412000) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling HER2 (red) with Pertuzumab (anti-HER2) (P412000). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Pertuzumab (anti-HER2) (P412000)

Pertuzumab (anti-HER2) (P412000) - SEC
The purity of Pertuzumab (anti-HER2) (P412000) is more than 95% verified by HPLC.

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参考文献

1. Badache A, Hynes NE. (2004) A new therapeutic antibody masks ErbB2 to its partners.. Cancer Cell, 5 (4): (299-301). [PMID:15093533]
2. Ferguson KM. (2004) Active and inactive conformations of the epidermal growth factor receptor.. Biochem Soc Trans, 32 (Pt 5): (742-5). [PMID:15494003]
3. Adams CW, Allison DE, Flagella K, Presta L, Clarke J, Dybdal N, McKeever K, Sliwkowski MX. (2006) Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab.. Cancer Immunol Immunother, 55 (6): (717-27). [PMID:16151804]
4. Harbeck N, Beckmann MW, Rody A, Schneeweiss A, Müller V, Fehm T, Marschner N, Gluz O, Schrader I, Heinrich G et al.. (2013) HER2 Dimerization Inhibitor Pertuzumab - Mode of Action and Clinical Data in Breast Cancer.. Breast Care (Basel), 8 (1): (49-55). [PMID:24715843]

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Pertuzumab (anti-HER2)

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库存信息

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基本信息

产品属性

数据库链接

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相关文档

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