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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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rp142386-10μg (试用装) 申请此免费试用装(?) 作为尊贵的客户,您每年可免费申请一次试用装产品,尽享探索与享受!
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10μg |
现货 ![]() |
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rp142386-50μg |
50μg |
现货 ![]() |
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rp142386-100μg |
100μg |
现货 ![]() |
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rp142386-1mg |
1mg |
期货 ![]() |
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产品名称 | Recombinant Human 4-1BB Ligand Protein |
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别名 | 41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; TNLG5A |
英文别名 | 41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; TNLG5A |
规格或纯度 | Animal Free, >95%(SDS-PAGE, HPLC), Active, E.coli, No tag, 71-254 aa |
产品介绍 |
Purity > 95 % by SDS-PAGE and HPLC analyses. Endotoxin level is less than 1 EU/µg. Function 4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. Cytokine that binds to TNFRSF9. This receptor contributes to the clonal expansion, survival, and development of T cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. |
生物活性 | Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml. |
纯度 | >95%(SDS-PAGE, HPLC) |
内毒素水平 | <1 EU/µg |
表达系统 | E.coli |
种属 | Human |
氨基酸 | 71-254 aa |
序列 | REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE |
蛋白标签 | No tag |
蛋白长度 | Protein fragment |
无动物源 | Yes |
Accession # | P41273 |
来源 | Recombinant |
预测分子量 | 19.4 kDa |
应用 | Active, SDS-PAGE |
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物理外观 | Lyophilized |
储存缓冲液 | Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4 |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio |
储存温度 | -20°C储存,避免反复冻融 |
运输条件 | 超低温冰袋运输 |
稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ℃ as supplied; 1 month, 2 to 8 ℃ under sterile conditions after reconstitution; 3 months, -20 to -70 ℃ under sterile conditions after reconstitu |
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Recombinant Human 4-1BB Ligand Protein (rp142386)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/mL, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.
Recombinant Human 4-1BB Ligand Protein (rp142386)-SDS-PAGE
Recombinant Human 4-1BB Ligand Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 19.4 kDa.