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Recombinant Human 4-1BB Ligand Protein

功能和特点
  • 规格或纯度: Animal Free, >95%(SDS-PAGE, HPLC), Active, E.coli, No tag, 71-254 aa
  • 生物活性: Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
  • 蛋白标签: No tag
  • 应用: Active, SDS-PAGE
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp142386-10μg (试用装)
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10μg 现货 Stock Image
rp142386-50μg
50μg 现货 Stock Image
rp142386-100μg
100μg 现货 Stock Image
rp142386-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human 4-1BB Ligand Protein
别名 41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; TNLG5A
英文别名 41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; TNLG5A
规格或纯度 Animal Free, >95%(SDS-PAGE, HPLC), Active, E.coli, No tag, 71-254 aa
产品介绍


Purity

> 95 % by SDS-PAGE and HPLC analyses. Endotoxin level is less than 1 EU/µg.


Function

4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. Cytokine that binds to TNFRSF9. This receptor contributes to the clonal expansion, survival, and development of T cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.

生物活性 Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
纯度 >95%(SDS-PAGE, HPLC)
内毒素水平 <1 EU/µg
表达系统 E.coli
种属 Human
氨基酸 71-254 aa
序列 REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE
蛋白标签 No tag
蛋白长度 Protein fragment
无动物源 Yes
Accession # P41273
来源 Recombinant
预测分子量 19.4 kDa

产品规格参数

应用 Active, SDS-PAGE
物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ℃ as supplied; 1 month, 2 to 8 ℃ under sterile conditions after reconstitution; 3 months, -20 to -70 ℃ under sterile conditions after reconstitu

质检证书(COA)

质检报告(COA)

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图片

Recombinant Human 4-1BB Ligand Protein (rp142386)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/mL, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.

Recombinant Human 4-1BB Ligand Protein (rp142386)-SDS-PAGE
Recombinant Human 4-1BB Ligand Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 19.4 kDa.

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FAQ
巨噬细胞刺激蛋白(MSP)
巨噬细胞刺激蛋白(MSP)
Macrophage Stimulating Protein (MSP)

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