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Recombinant Human ARMET/ARP Protein

功能和特点
  • 规格或纯度: Animal Free, >95%(SDS-PAGE and HPLC), Active, E.coli, No tag, 25-182aa
  • 生物活性: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.
  • 蛋白标签: No tag
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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp142973-10μg (试用装)
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10μg 现货 Stock Image
rp142973-50μg
50μg 现货 Stock Image
rp142973-100μg
100μg 现货 Stock Image
rp142973-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human ARMET/ARP Protein
别名 重组人 ARMET/ARP 蛋白; Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic f
英文别名 Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MG
规格或纯度 Animal Free, >95%(SDS-PAGE and HPLC), Active, E.coli, No tag, 25-182aa
产品介绍


Purity
>95% by SDS-PAGE and HPLC analyses.

Function
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.

Post-translational
May contain sialic acid residues.

生物活性 Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.
内毒素水平 <1.0 EU/μg
表达系统 E.coli
种属 Human
氨基酸 25-182aa
序列 LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
蛋白标签 No tag
蛋白长度 Full length protein
无动物源 Yes
Accession # P55145
来源 Recombinant
预测分子量 18.2 kDa
SDS-PAGE 18.2 kDa

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportio
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconst

质检证书(COA)

质检报告(COA)

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图片

Recombinant Human ARMET/ARP Protein (rp142973)-Protein Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/mL, corresponding to a specific activity of > 50 IU/mg.

Recombinant Human ARMET/ARP Protein (rp142973)-SDS-PAGE
Recombinant Human ARMET/ARP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining. Showing a band at 18.2 kDa under reducing conditions and 16.8 kDa under non-reducing conditions.

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