Recombinant Human CCL18 Protein

功能和特点

规格或纯度: Carrier Free, ＞96%(SDS-PAGE,HPLC), Active, E.coli, No tag, 22-89 aa
蛋白标签: No tag

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货号 (SKU)	包装规格	是否现货
rp143731-10μg (试用装) 申请此免费试用装（?）作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！	10μg	现货
rp143731-50μg	50μg	现货
rp143731-100μg	100μg	现货
rp143731-1mg	1mg	期货

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基本描述

产品名称	Recombinant Human CCL18 Protein
别名	Human Macrophage Inflammatory Protein-4, Alternative macrophage activation-associated CC chemokine 1; AMAC-1; AMAC1; CC chemokine ligand 18; AMAC-1Small-inducible cytokine A18; CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); C
英文别名	Human Macrophage Inflammatory Protein-4, Alternative macrophage activation-associated CC chemokine 1; AMAC-1; AMAC1; CC chemokine ligand 18; AMAC-1Small-inducible cytokine A18; CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); C
规格或纯度	Carrier Free, ＞96%(SDS-PAGE,HPLC), Active, E.coli, No tag, 22-89 aa
产品介绍	Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell mediated immunity responses. Recombinant Human MIP-4/CCL18 is a 7.9kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Purity >96% SDS-PAGE Function Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
纯度	＞96%(SDS-PAGE,HPLC)
内毒素水平	＜0.1 EU/μg
表达系统	E.coli
种属	Human
氨基酸	22-89aa
序列	QVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQICA DPNKKWVQKYISDLKLNA
蛋白标签	No tag
无载体	Yes
Accession #	P55774
预测分子量	7.9kDa
SDS-PAGE	9.5 kDa, under reducing conditions; 12.0 kDa, under non-reducing conditions.

产品规格参数

物理外观	Lyophilized
储存缓冲液	Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.0
复溶	1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom。 2、 Reconstitute in a sterile aqueous buffer to an appropriate concentration。
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Shipped at 4°C. Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.0. Store at -80°C. Avoid freeze / thaw cycle

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Protein Bioactivity: Recombinant Human CCL18 Protein (rp143731)

Recombinant Human CCL18 Protein (rp143731) - Protein Bioactivity
The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/mL.

SDS-PAGE: Recombinant Human CCL18 Protein (rp143731)

Recombinant Human CCL18 Protein (rp143731) - SDS-PAGE
2.5μg/lane of Recombinant Human CCL18 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 9.5 kDa under reducing conditions and 12.0 kDa under non-reducing conditions.

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Recombinant Human CCL18 Protein

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基本描述

产品规格参数

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