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Recombinant Human Cardiotrophin-1 Protein

Recombinant Human Cardiotrophin-1 Protein

功能和特点

规格或纯度: Animal Free, >95%(SDS-PAGE), Active, HEK293, No tag, 2-201 aa
蛋白标签: No tag

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货号 (SKU)	包装规格	是否现货
rp144781-10μg (试用装) 申请此免费试用装（?）作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！	10μg	现货
rp144781-50μg	50μg	现货
rp144781-100μg	100μg	现货
rp144781-1mg	1mg	期货

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基本描述

产品名称	Recombinant Human Cardiotrophin-1 Protein
别名	cardiophin 1; Cardiophin1; cardiotrophin 1; Cardiotrophin1; CardiotrophinI; Cardiotrophin-1; CT-1; CT1; CT 1; CTF1; CTF 1; Ctf1; CTF1_HUMAN; 重组人CT-1蛋白; 重组人心肌营养素1蛋白;
英文别名	cardiophin 1; Cardiophin1; cardiotrophin 1; Cardiotrophin1; CardiotrophinI; Cardiotrophin-1; CT-1; CT1; CT 1; CTF1; CTF 1; Ctf1; CTF1_HUMAN;
规格或纯度	Animal Free, >95%(SDS-PAGE), Active, HEK293, No tag, 2-201 aa
产品介绍	Purity >95% SDS-PAGE Function Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Background Cardiotrophin-1 (CT-1) is a member of the cytokine family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). It was originally isolated based on its ability to induce cardiac myocyte hypertrophy in vitro. CT-1 has since been shown to be a pleiotrophic cytokine with overlapping actions with other IL-6 family members on a variety of cell types. Human CT-1 encodes a 201 amino acid (aa) residue protein that lacks a hydrophobic signal peptide. The mechanism of CT-1 release from cells is currently not understood. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity. CT-1 is highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels of CT-1 expression is also seen in testis and brain. CT-1 initiates downstream signaling pathways through the heterodimerization of gp130 and the LIF receptor beta subunit. A third alpha receptor subunit has been implicated in the receptor complex.
纯度	＞95%(SDS-PAGE)
内毒素水平	< 1.0 EU/μg
表达系统	HEK293 Cells
种属	Human
氨基酸	2-201 aa
序列	GPSRREGSLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLLDAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAALGAANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQLLPGGSA
蛋白标签	No tag
无动物源	Yes
Accession #	Q16619
预测分子量	21.2 kDa
SDS-PAGE	27.2 kDa, under reducing conditions; 27.2 kDa, under non-reducing conditions.

产品规格参数

物理外观	Lyophilized
储存缓冲液	Lyophilized from sterile PBS, 10% Glycerol, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.
复溶	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25mg/mL.
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

图片

Protein Bioactivity: Recombinant Human Cardiotrophin-1 Protein (rp144781)

Recombinant Human Cardiotrophin-1 Protein (rp144781)- Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically less than 10 ng/mL.

SDS-PAGE: Recombinant Human Cardiotrophin-1 Protein (rp144781)

Recombinant Human Cardiotrophin-1 Protein (rp144781) - SDS-PAGE
2 μg/lane of Recombinant Human Cardiotrophin-1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 27.2 kDa.

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Recombinant Human Cardiotrophin-1 Protein

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基本描述

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