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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
rp147441-10μg |
10μg | 期货 | | |
rp147441-50μg |
50μg | 期货 | | |
rp147441-100μg |
100μg | 期货 | | |
rp147441-1mg |
1mg | 期货 | |
产品名称 | Recombinant Human IL-17RA/IL-17R Protein |
---|---|
别名 | 重组人白细胞介素17受体蛋白; CD217 antigen; CD217; Cdw217; CDw217interleukin 17 receptor; hIL-17R; IL-17 R; IL-17 RA; IL-17 receptor A; IL17RA; IL-17RA; IL-17RAMGC10262; IL17Rinterleukin-17 receptor A; interleukin 17 receptor A; CANDF5; MGC10262; IMD51 |
英文别名 | CD217 antigen; CD217; Cdw217; CDw217interleukin 17 receptor; hIL-17R; IL-17 R; IL-17 RA; IL-17 receptor A; IL17RA; IL-17RA; IL-17RAMGC10262; IL17Rinterleukin-17 receptor A; interleukin 17 receptor A; CANDF5; MGC10262; IMD51 |
规格或纯度 | Animal Free,>95%(SDS-PAGE), Active, 293F, Fc&His, 33-320aa |
产品介绍 |
Purity >95% SDS-PAGE Function Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. |
纯度 | >95%(SDS-PAGE) |
内毒素水平 | <0.01 EU/μg |
表达系统 | 293F |
种属 | Human |
氨基酸 | 33 to 320 aa |
序列 | LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFF |
蛋白标签 | Fc, 6×His tag at the C-terminus |
无动物源 | Yes |
Accession # | Q96F46 |
预测分子量 | 60 kDa |
物理外观 | Lyophilized |
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储存缓冲液 | PBS(PH7.4), containing 5% trehalose, 5% mannitol |
复溶 | Reconstitute in water to a concentration of 0.1-1.0 mg/ml. |
储存温度 | -20°C储存 |
运输条件 | 冰袋运输 |
稳定性与储存 | 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitution. |
输入批号以搜索COA:
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Protein Bioactivity
Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED₅₀ for this effect is 0.08 µg/mL in the presence of 10 ng/mL recombinant human IL-17.
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Binding ELISA
IL-17RA/IL-17R Protein (rp147441) was serially diluted 3-fold and coated on a Clear Polystyrene Microplate (W291037) can bind Brodalumab (anti-IL17RA) (Ab169276). The EC₅₀ for this effect is 5.5 ng/mL.
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - SDS-PAGE
2 μg/lane of Recombinant Human IL-17RA/IL-17R was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 91.3 kDa under reducing conditions and 208.1 kDa under non-reducing conditions.