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Recombinant Human IL-21 Protein

功能和特点
  • 规格或纯度: Animal Free, >97% (SDS-PAGE, HPLC), Active, E.coli, No tag, 30-162 aa
  • 蛋白标签: No tag
有货

库存信息

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库存信息

关闭

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp147498-20μg
20μg 现货 Stock Image
rp147498-100μg
100μg 现货 Stock Image
rp147498-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-21 Protein
别名 CVID11;IL21;IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform; Za11; 重组人IL-21蛋白
英文别名 CVID11; IL21; IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform; Za11
规格或纯度 Animal Free, >97% (SDS-PAGE, HPLC), Active, E.coli, No tag, 30-162 aa
产品介绍


Purity

>97%(SDS-PAGE,HPLC)


Function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

纯度 >97% (SDS-PAGE, HPLC)
内毒素水平 <0.01 EU/μg
表达系统 E.coli
种属 Human
氨基酸 Gln30-Ser162
序列 QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
蛋白标签 No tag
无动物源 Yes
Accession # Q9HBE4
预测分子量 15.4 kDa
SDS-PAGE 13.9 kDa, under reducing conditions; 13.9 kDa, under non-reducing conditions.

产品规格参数

物理外观 Lyophilized
储存缓冲液 Lyophilized from a 0.2μm filtered solution 20mM PBS, pH 7.4
复溶 This vial must be briefly centrifuged prior to opening to bring the - 2 - contents to the bottom. Reconstitute in a sterile aqueous buffer to an appropriate concentration. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C
储存温度 -20°C储存
运输条件 超低温冰袋运输
稳定性与储存 For long term storage, the product should be stored ≤ -20°C. Please avoid repeated freeze-thaw cycles after reconstitution. 12 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution

质检证书(COA)

质检报告(COA)

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图片

Recombinant Human IL-21 Protein (rp147498) - Protein Bioactivity
Recombinant Human IL-21 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED₅₀ for this effect is typically less than 40 ng/mL.

Recombinant Human IL-21 Protein (rp147498) - Protein Bioactivity
Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED₅₀ for this effect is less than 2.0 ng/mL.

Recombinant Human IL-21 Protein (rp147498) - SDS-PAGE
2 μg/lane of Recombinant Human IL-21 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 13.9 kDa.

产品问答

产品问答

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