Recombinant Human Nectin-3 Protein

功能和特点

规格或纯度: Animal Free, >98%(SDS-PAGE), Active, HEK293, His tag, 58-400 aa
蛋白标签: His tag at the C-terminus

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货号 (SKU)	包装规格	是否现货
rp149161-10μg (试用装) 申请此免费试用装（?）作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！	10μg	现货
rp149161-50μg	50μg	现货
rp149161-100μg	100μg	现货
rp149161-1mg	1mg	期货

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基本描述

产品名称	Recombinant Human Nectin-3 Protein
别名	CD113 antigen; CD113; CDw113FLJ90624; DKFZp566B0846; nectin 3; Nectin3; Nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3CD113; PVRL3; PVRR3; PRR3; PVRR3; CDW113; NECTIN-3
英文别名	CD113 antigen; CD113; CDw113FLJ90624; DKFZp566B0846; nectin 3; Nectin3; Nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3CD113; PVRL3; PVRR3; PRR3; PVRR3; CDW113; NECTIN-3
规格或纯度	Animal Free, >98%(SDS-PAGE), Active, HEK293, His tag, 58-400 aa
产品介绍	Purity >98% SDS-PAGE. Function Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
纯度	＞98%(SDS-PAGE)
内毒素水平	< 1.0 EU/μg
表达系统	HEK293 Cells
种属	Human
氨基酸	58-400 aa
序列	GPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWP
蛋白标签	His tag at the C-terminus
无动物源	Yes
Accession #	Q9NQS3
预测分子量	39.3 kDa
SDS-PAGE	71.1 kDa, under reducing conditions; 68.0 kDa, under non-reducing conditions.

产品规格参数

物理外观	Lyophilized
储存缓冲液	Lyophilized from sterile PBS, pH7.4, 5% Trehalose, 5% Mannitol.
复溶	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.59mg/mL.
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.

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Protein Bioactivity: Recombinant Human Nectin-3 Protein (rp149161)

Recombinant Human Nectin-3 Protein (rp149161) - Protein Bioactivity
Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.

SDS-PAGE: Recombinant Human Nectin-3 Protein (rp149161)

Recombinant Human Nectin-3 Protein (rp149161) - SDS-PAGE
2.5μg/lane of Recombinant Human Nectin-3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 71.1 kDa under reducing conditions and 68.0 kDa under non-reducing conditions.

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Recombinant Human Nectin-3 Protein

库存信息

库存信息

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库存信息

基本描述

产品规格参数

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