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Recombinant Mouse CD14 Protein

功能和特点
  • 规格或纯度: Animal Free, >95%(SDS-PAGE), Active, 293F, Fc&His, 18-345aa
  • 蛋白标签: Fc, 6×His tag at the C-terminu
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp153710-2μg
2μg 期货 Stock Image
rp153710-10μg
10μg 期货 Stock Image
rp153710-100μg
100μg 期货 Stock Image
rp153710-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Mouse CD14 Protein
别名 重组小鼠单核细胞分化抗原CD14蛋白; CD 14; CD_antigen=CD14; CD14; CD14 antigen; CD14 molecule; CD14_HUMAN; LPS-R; Mo2; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14 urinary form; Monocyte differentiation antigen CD14, membrane-bound form;
英文别名 CD 14; CD_antigen=CD14; CD14; CD14 antigen; CD14 molecule; CD14_HUMAN; LPS-R; Mo2; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14 urinary form; Monocyte differentiation antigen CD14, membrane-bound form; Myeloid cell specifi
规格或纯度 Animal Free, >95%(SDS-PAGE), Active, 293F, Fc&His, 18-345aa
产品介绍


Purity

>90% SDS-PAGE.


Additional sequence information

This product is for the mature full length protein. The signal peptide is not included. NP_033971


Function

Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.


Post-translational

N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.

纯度 >95%(SDS-PAGE)
内毒素水平 <0.01 EU/μg
表达系统 293F
种属 Mouse
氨基酸 18 to 345
序列 APPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQL
蛋白标签 Fc, 6×His tag at the C-terminu
无动物源 Yes
Accession # Q4FJP7
预测分子量 62 kDa

产品规格参数

物理外观 Lyophilized
储存缓冲液 PBS(PH7.4) containing 5% trehalose, 5% mannitol
复溶 Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitution.

质检证书(COA)

质检报告(COA)

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图片

Recombinant Mouse CD14 Protein (rp153710) - Protein Bioactivity
Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED₅₀ for this effect is 2.2 µg/mL.

Recombinant Mouse CD14 Protein (rp153710) - SDS-PAGE
2 μg/lane of Recombinant Mouse CD14 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 85.5 kDa under reducing conditions and 195.7 kDa under non-reducing conditions.

产品问答

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