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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
---|---|---|---|---|
rp153710-2μg |
2μg |
期货 ![]() |
| |
rp153710-10μg |
10μg |
期货 ![]() |
| |
rp153710-100μg |
100μg |
期货 ![]() |
| |
rp153710-1mg |
1mg |
期货 ![]() |
|
产品名称 | Recombinant Mouse CD14 Protein |
---|---|
别名 | 重组小鼠单核细胞分化抗原CD14蛋白; CD 14; CD_antigen=CD14; CD14; CD14 antigen; CD14 molecule; CD14_HUMAN; LPS-R; Mo2; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14 urinary form; Monocyte differentiation antigen CD14, membrane-bound form; |
英文别名 | CD 14; CD_antigen=CD14; CD14; CD14 antigen; CD14 molecule; CD14_HUMAN; LPS-R; Mo2; Monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14 urinary form; Monocyte differentiation antigen CD14, membrane-bound form; Myeloid cell specifi |
规格或纯度 | Animal Free, >95%(SDS-PAGE), Active, 293F, Fc&His, 18-345aa |
产品介绍 |
Purity >90% SDS-PAGE. Additional sequence information This product is for the mature full length protein. The signal peptide is not included. NP_033971 Function Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. Post-translational N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
纯度 | >95%(SDS-PAGE) |
内毒素水平 | <0.01 EU/μg |
表达系统 | 293F |
种属 | Mouse |
氨基酸 | 18 to 345 |
序列 | APPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQL |
蛋白标签 | Fc, 6×His tag at the C-terminu |
无动物源 | Yes |
Accession # | Q4FJP7 |
预测分子量 | 62 kDa |
物理外观 | Lyophilized |
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储存缓冲液 | PBS(PH7.4) containing 5% trehalose, 5% mannitol |
复溶 | Reconstitute in water to a concentration of 0.1-1.0 mg/ml. |
储存温度 | -20°C储存,避免反复冻融 |
运输条件 | 超低温冰袋运输 |
稳定性与储存 | 12 months from date of receipt, -20 to -70 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, -20 to -70 ℃ under sterile conditions after reconstitution. |
输入批号以搜索COA:
Recombinant Mouse CD14 Protein (rp153710) - Protein Bioactivity
Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED₅₀ for this effect is 2.2 µg/mL.
Recombinant Mouse CD14 Protein (rp153710) - SDS-PAGE
2 μg/lane of Recombinant Mouse CD14 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 85.5 kDa under reducing conditions and 195.7 kDa under non-reducing conditions.