Recombinant Rat SCF Protein

功能和特点

规格或纯度: Animal Free, >95% (SDS-PAGE), Active, E.coli, His-tag, 26-189 aa
蛋白标签: C-terminal His tag

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
rp155217-10μg (试用装) 申请此免费试用装（?）作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！	10μg	现货
rp155217-50μg	50μg	现货
rp155217-100μg	100μg	现货
rp155217-1mg	1mg	期货

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

产品名称	Recombinant Rat SCF Protein
别名	c-kit Ligand; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; KIT ligand; Kitl; KITLG; KL-1; Mast cell growth factor; MGF; MGFSHEP7; SCF; SCFStem cell factor; SFc-Kit ligand; SHEP7; SLF; steel factor; C kit ligand; C-kit
英文别名	c-kit Ligand; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; KIT ligand; Kitl; KITLG; KL-1; Mast cell growth factor; MGF; MGFSHEP7; SCF; SCFStem cell factor; SFc-Kit ligand; SHEP7; SLF; steel factor; C kit ligand; C-kit
规格或纯度	Animal Free, >95% (SDS-PAGE), Active, E.coli, His-tag, 26-189 aa
产品介绍	Purity >95% SDS-PAGE. Additional sequence information A single non-glycosylated polypeptide chain. Function Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. Post-translational A soluble form (sKITLG) is produced by proteolytic processing of isoform 1 in the extracellular domain. Found in two differentially glycosylated forms, LMW-SCF and HMW-SCF. LMW-SCF is fully N-glycosylated at Asn-145, partially N-glycosylated at Asn-90, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97 or Asn-118. HMW-SCF is N-glycosylated at Asn-118, Asn-90 and Asn-145, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97. A soluble form exists as a cleavage product of the extracellular domain.
纯度	＞95% (SDS-PAGE)
内毒素水平	< 1 EU/μg
表达系统	E.coli
种属	Rat
氨基酸	26-189 aa
序列	QEICRNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVTHLSVSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVACMEENAPKNVKESLKKPETRNFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVAHHHHHH
蛋白标签	C-terminal His tag
无动物源	Yes
Accession #	P21581
预测分子量	18 kDa
SDS-PAGE	17.2 kDa, under reducing conditions; 15.0 kDa, under non-reducing conditions.

产品规格参数

物理外观	Lyophilized
储存缓冲液	Lyophilized from PBS, pH 7.4, 5% Trehalose, 5% Mannitol
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -20~-80℃ for more than 1 year

图片

Protein Bioactivity: Recombinant Rat SCF Protein (rp155217)

Recombinant Rat SCF Protein (rp155217) - Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically less than 15.72 ng/mL.

SDS-PAGE: Recombinant Rat SCF Protein (rp155217)

Recombinant Rat SCF Protein (rp155217) - SDS-PAGE
2.5 μg/lane of Recombinant Rat SCF Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 17.2 kDa under reducing conditions and 15.0 kDa under non-reducing conditions.

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

卷

分子量

g/mol

稀释计算器

计算制备储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)）

浓度 2 (C2)

体积 2 (V2)）

重组计算器

重建计算器允许您快速计算试剂的体积，以重建小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的重组浓度

Recombinant Rat SCF Protein

库存信息

库存信息

库存信息

库存信息

基本描述

产品规格参数

质检证书(COA)

质检报告(COA)

图片

相关文档

产品问答

产品问答

计算器

摩尔浓度计算器

稀释计算器

重组计算器