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IL-31

功能和特点
有货

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
rp174304-500μg
500μg 期货 Stock Image
rp174304-1mg
1mg 期货 Stock Image
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Interleukin-31 receptor Agonist

基本描述

产品名称 IL-31
别名 interleukin-31
英文别名 interleukin-31

产品规格参数

CAS编号和信息 rp174304

质检证书(COA)

质检报告(COA)

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产品问答

产品问答

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参考文献

1. Sonkoly E, Muller A, Lauerma AI, Pivarcsi A, Soto H, Kemeny L, Alenius H, Dieu-Nosjean MC, Meller S, Rieker J et al..  (2006)  IL-31: a new link between T cells and pruritus in atopic skin inflammation..  J Allergy Clin Immunol,  117  (2):  (411-7).  [PMID:16461142]
2. Lee CH, Yu HS.  (2011)  Biomarkers for itch and disease severity in atopic dermatitis..  Curr Probl Dermatol,  41  (13):  (136-48).  [PMID:21576954]
3. Cornelissen C, Lüscher-Firzlaff J, Baron JM, Lüscher B.  (2012)  Signaling by IL-31 and functional consequences..  Eur J Cell Biol,  91  (6-7):  (552-66).  [PMID:21982586]
4. Kim S, Kim HJ, Yang HS, Kim E, Huh IS, Yang JM.  (2011)  IL-31 Serum Protein and Tissue mRNA Levels in Patients with Atopic Dermatitis..  Ann Dermatol,  23  (4):  (468-73).  [PMID:22148014]
5. Baron JM, Lüscher B.  (2012)  IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis..  Acta Derm Venereol,  92  (1):  (5-6).  [PMID:22215012]
6. Lewis KE, Holdren MS, Maurer MF, Underwood S, Meengs B, Julien SH, Byrnes-Blake KA, Freeman JA, Bukowski TR, Wolf AC et al..  (2017)  Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL-31 neutralizing antibody..  J Eur Acad Dermatol Venereol,  31  (1):  (142-150).  [PMID:27501029]
7. Storan ER, O'Gorman SM, McDonald ID, Steinhoff M.  (2015)  Role of cytokines and chemokines in itch..  Handb Exp Pharmacol,  226  (13):  (163-76).  [PMID:25861779]
8. Nemoto O, Furue M, Nakagawa H, Shiramoto M, Hanada R, Matsuki S, Imayama S, Kato M, Hasebe I, Taira K et al..  (2016)  The first trial of CIM331, a humanized antihuman interleukin-31 receptor A antibody, in healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomized, double-blind, placebo-controlled study..  Br J Dermatol,  174  (2):  (296-304).  [PMID:26409172]

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