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IL-6

功能和特点
有货

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
rp174314-500μg
500μg 期货 Stock Image
rp174314-1mg
1mg 期货 Stock Image

基本描述

产品名称 IL-6
别名 B-cell stimulatory factor 2;CTL differentiation factor;hybridoma growth factor;interferon β2;interleukin-6
英文别名 B-cell stimulatory factor 2;CTL differentiation factor;hybridoma growth factor;interferon β2;interleukin-6

产品规格参数

CAS编号和信息 rp174314

质检证书(COA)

质检报告(COA)

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产品问答

产品问答

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参考文献

1. Morjaria JB, Babu KS, Vijayanand P, Chauhan AJ, Davies DE, Holgate ST.  (2011)  Sputum IL-6 concentrations in severe asthma and its relationship with FEV1..  Thorax,  66  (6):  (537).  [PMID:20880874]
2. Scheller J, Chalaris A, Schmidt-Arras D, Rose-John S.  (2011)  The pro- and anti-inflammatory properties of the cytokine interleukin-6..  Biochim Biophys Acta,  1813  (5):  (878-88).  [PMID:21296109]
3. Ferreira MA, Matheson MC, Duffy DL, Marks GB, Hui J, Le Souëf P, Danoy P, Baltic S, Nyholt DR, Jenkins M et al..  (2011)  Identification of IL6R and chromosome 11q13.5 as risk loci for asthma..  Lancet,  378  (9795):  (1006-14).  [PMID:21907864]
4. Uddin M, Lau LC, Seumois G, Vijayanand P, Staples KJ, Bagmane D, Cornelius V, Dorinsky P, Davies DE, Djukanović R.  (2013)  EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma..  PLoS ONE,  (9):  (e72502).  [PMID:24039773]
5. Genovese MC, Fleischmann R, Furst D, Janssen N, Carter J, Dasgupta B, Bryson J, Duncan B, Zhu W, Pitzalis C et al..  (2014)  Efficacy and safety of olokizumab in patients with rheumatoid arthritis with an inadequate response to TNF inhibitor therapy: outcomes of a randomised Phase IIb study..  Ann Rheum Dis,  73  (9):  (1607-15).  [PMID:24641941]
6. Engler H, Brendt P, Wischermann J, Wegner A, Röhling R, Schoemberg T, Meyer U, Gold R, Peters J, Benson S et al..  (2017)  Selective increase of cerebrospinal fluid IL-6 during experimental systemic inflammation in humans: association with depressive symptoms..  Mol Psychiatry,  22  (10):  (1448-1454).  [PMID:28138158]
7. Takeuchi T, Tanaka Y, Yamanaka H, Amano K, Nagamine R, Park W, Shiozawa K, Tsukano M, Wei JC, Shao J et al..  (2016)  Efficacy and safety of olokizumab in Asian patients with moderate-to-severe rheumatoid arthritis, previously exposed to anti-TNF therapy: Results from a randomized phase II trial..  Mod Rheumatol,  26  (1):  (15-23).  [PMID:26358841]
8. Sun Y, Wang D, Salvadore G, Hsu B, Curran M, Casper C, Vermeulen J, Kent JM, Singh J, Drevets WC et al..  (2017)  The effects of interleukin-6 neutralizing antibodies on symptoms of depressed mood and anhedonia in patients with rheumatoid arthritis and multicentric Castleman's disease..  Brain Behav Immun,  66  (13):  (156-164).  [PMID:28676350]
9. Garbers C, Heink S, Korn T, Rose-John S.  (2018)  Interleukin-6: designing specific therapeutics for a complex cytokine..  Nat Rev Drug Discov,  17  (6):  (395-412).  [PMID:29725131]
10. Bhaskar S, Sinha A, Banach M, Mittoo S, Weissert R, Kass JS, Rajagopal S, Pai AR, Kutty S.  (2020)  Cytokine Storm in COVID-19-Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper..  Front Immunol,  11  (13):  (1648).  [PMID:32754159]
11. Hu B, Huang S, Yin L.  (2021)  The cytokine storm and COVID-19..  J Med Virol,  93  (1):  (250-256).  [PMID:32592501]
12. Yokoyama A, Kohno N, Fujino S, Hamada H, Inoue Y, Fujioka S, Ishida S, Hiwada K.  (1995)  Circulating interleukin-6 levels in patients with bronchial asthma..  Am J Respir Crit Care Med,  151  (5):  (1354-8).  [PMID:7735584]
13. Shaw S, Bourne T, Meier C, Carrington B, Gelinas R, Henry A, Popplewell A, Adams R, Baker T, Rapecki S et al..  (2014)  Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling..  MAbs,  (3):  (774-82).  [PMID:24670876]

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