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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp174805-500μg |
500μg |
期货  |
| |
| rp174805-1mg |
1mg |
期货 |
|
| 产品名称 | programmed cell death 1 ligand 1 |
|---|---|
| 别名 | B7 homolog 1;B7-H1;PD-L1;PDL1;programmed death ligand 1 |
| 英文别名 | B7 homolog 1;B7-H1;PD-L1;PDL1;programmed death ligand 1 |
| CAS编号和信息 | rp174805 |
|---|
| Ensembl Gene | ENSG00000120217 |
|---|---|
| Entrez Gene | 29126 |
| OMIM | 605402 |
| RefSeq Nucleotide | NM_014143 |
| RefSeq Protein | NP_054862 |
| UniProtKB | Q9NZQ7 |
| CATH/Gene3D | 2.60.40.10 |
输入批号以搜索COA:
| 1. Janakiram M, Abadi YM, Sparano JA, Zang X. (2012) T cell coinhibition and immunotherapy in human breast cancer.. Discov Med, 14 (77): (229-36). [PMID:23114578] |
| 2. Greaves P, Gribben JG. (2013) The role of B7 family molecules in hematologic malignancy.. Blood, 121 (5): (734-44). [PMID:23223433] |
| 3. Tang PA, Heng DY. (2013) Programmed death 1 pathway inhibition in metastatic renal cell cancer and prostate cancer.. Curr Oncol Rep, 15 (2): (98-104). [PMID:23263823] |
| 4. Lu J, Lee-Gabel L, Nadeau MC, Ferencz TM, Soefje SA. (2015) Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy.. J Oncol Pharm Pract, 21 (6): (451-67). [PMID:24917416] |
| 5. Johnson DB, Rioth MJ, Horn L. (2014) Immune checkpoint inhibitors in NSCLC.. Curr Treat Options Oncol, 15 (4): (658-69). [PMID:25096781] |
| 6. Sasikumar PG, Ramachandra M. (2017) Small-molecule antagonists of the immune checkpoint pathways: concept to clinic.. Future Med Chem, 9 (12): (1305-1308). [PMID:28771036] |
| 7. Miao X, Xu R, Fan B, Chen J, Li X, Mao W, Hua S, Li B. (2018) PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin.. Sci Rep, 8 (1): (1605). [PMID:29371688] |
| 8. Guzik K, Zak KM, Grudnik P, Magiera K, Musielak B, Törner R, Skalniak L, Dömling A, Dubin G, Holak TA. (2017) Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.. J Med Chem, 60 (13): (5857-5867). [PMID:28613862] |
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