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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S115193-25mg |
25mg |
现货  |
| |
| S115193-100mg |
100mg |
现货 |
|
| 别名 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione; (±)-Alkannin ;(±)-Shikalkin; (±)-Shikonin; (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; |
|---|---|
| 英文别名 | 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione; (±)-Alkannin ;(±)-Shikalkin; (±)-Shikonin; (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; |
| 规格或纯度 | 分析标准品，≥98% |
| 英文名称 | Shikonin |
| 生化机理 | Shikonin is a naturally occurring active chemical found in the root of Lithospermum erythrorhizon and used as a Chinese herb. The compound is a naphthoquinone derivative and has been shown to have anti-inflammatory and anti-tumor properties, as well as alter chemokine expression and function. Angiogenesis studies have shown that Shikonin can inhibit proliferation and migration of endothelial cells, block integrin αvβ3 expression, and inhibit B16 melanoma- and tumor necrosis factor-alpha-inuced angiogenesis in mice. Shikonin can down-regulate protein and mRNA expression of CKR-5 (CCR5), a primary HIV-1 coreceptor, in macrophages in HIV studies. Shikonin is an inhibitor of PKM2. |
| 应用 | A naphthoquinone derivative with angiogenesis inhibitor properties. |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
A naphthoquinone derivative with angiogenesis inhibitor properties. A naphthoquinone derivative with angiogenesis inhibitor properties. |
| IUPAC Name | 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione |
|---|---|
| INCHI | InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1 |
| InChi Key | NEZONWMXZKDMKF-SNVBAGLBSA-N |
| Canonical SMILES | CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C |
| PubChem CID | 479503 |
| 分子量 | 288.3 |
| 溶解性 | Soluble in DMSO (10 mg/ml). |
|---|---|
| 密度 | 1.373 |
| 象形图 |
Harmful |
|---|---|
| 信号词 | Warning |
| 危险声明 |
H412: Harmful to aquatic life with long lasting effects H302: Harmful if swallowed |
| 预防措施声明 | P273,P501,P264,P270,P301+P312+P330 |
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